QoL · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
The review found no eligible studies for this question.
1 finding from 1 review
Healing of osteonecrosis - healed ('healed' vs 'improved', 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - healed ('healed' vs 'improved',… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.
5 findings from 1 review
RR 1.56 [0.77, 3.18]
1 study · 46 participants
GRADE not reported
RR 1.00 [0.25, 4.00]
1 study · 18 participants
GRADE not reported
RR 0.95 [0.44, 2.04]
1 study · 40 participants
GRADE not reported
Show 2 more findings
Adverse effects · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
Adverse effects: exacerbation of symptoms · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether dietary supplements (Catuama herbal compound) changes adverse effects: exacerbation of symptoms compared with placebo (very low certainty).
1 finding from 1 review
Incidence of respiratory diseases and pneumonia · Nursing home residents (mean age 78.3 to 86.0 years; more than 66% women; 62.1% to 87.3% with dental prostheses)
The review found no eligible studies for this question.
1 finding from 1 review
Denture-induced stomatitis · Residents of institutions for elderly people (nursing staff and residents took part in the education programme)
1 finding from 1 review
Schou 1989 (114 residents, unclear risk of bias): no difference in the prevalence of denture stomatitis between the groups.
1 study · 114 participants
GRADE not reported
Clinical resolution (oral lesion not completely resolved) · People with a diagnosis of oral leukoplakia
1 finding from 1 review
Adverse effects of pain treatment · Adolescents and adults undergoing orthodontic treatment
The review found no eligible studies for this question.
1 finding from 1 review
Somnolence · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether dietary supplements (Catuama herbal compound) changes adverse effects: drowsiness compared with placebo (very low certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
1 finding from 1 review
Patient‐reported pain intensity or pain relief: VAS (1 mm to 100 mm) ‐ 24 hours. Assumed risk: Not measured. Corresponding risk: not estimable. 39 participants (1 RCT). Quality: very low. Comments: insufficient…
1 study · 39 participants
Very low
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents and adults undergoing orthodontic treatment
Vibratory stimulation (vibratory adjuncts) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no vibration or placebo vibration; GRADE not reported.
5 findings from 1 review
MD 1.28 [-3.16, 5.71]
3 studies · 154 participants
GRADE not reported
MD -0.52 [-9.41, 8.36]
2 studies · 115 participants
GRADE not reported
Lobre 2015 (high risk of bias): mean overall pain intensity 8.49 mm lower on the VAS during the second month (P = 0.04) and 6.26 mm lower during the fourth month (P = 0.03); no evidence of benefit at month one or month…
2 studies
GRADE not reported
Show 2 more findings
Somnolence · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether benzodiazepines (topical clonazepam) changes adverse effects: drowsiness compared with placebo (very low certainty).
1 finding from 1 review
Denture plaque · Residents of institutions for elderly people (nursing staff and residents took part in the education programme)
1 finding from 1 review
One study (Schou 1989), at unclear risk of bias and analysing 114 residents, provided insufficient evidence to determine whether denture plaque scores are lower when educating residents or nursing staff without…
1 study · 114 participants
GRADE not reported
Clinical resolution (oral lesion not completely resolved) · People with a diagnosis of oral leukoplakia
1 finding from 1 review
SoF 4, Clinical resolution (not completely resolved) at 3 to 6 months: '3 studies (freeze-dried black raspberry gel, green tea extract capsules, mixed tea) did not find evidence of benefit.' No GRADE. Effects text:…
4 studies
GRADE not reported
Oral health · Nursing home residents (mean age 78.3 to 86.0 years; more than 66% women; 62.1% to 87.3% with dental prostheses)
The review found no eligible studies for this question.
1 finding from 1 review
SoF row 'Oral health': Illustrative risks -, relative effect -, participants/studies -, quality -; Comment: Outcome not reported. Not measured in any included study.
0 studies
No studies found
Adverse effects: dry mouth · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether benzodiazepines (topical clonazepam) changes adverse effects: dry mouth compared with placebo (very low certainty).
1 finding from 1 review
Improvement of histological features (not improved) · People with a diagnosis of oral leukoplakia
Systemic beta carotene or carotenoids (incl. lycopene) may leads to lower improvement of histological features (not improved) compared with placebo or no treatment (low certainty).
1 finding from 1 review
Improvement of histological features (not improved) · People with a diagnosis of oral leukoplakia
1 finding from 1 review
SoF 6, Histological changes: 'Not measured'. Effects text: data on histological changes from Armstrong 2013 were not available for analysis, but study authors reported no statistically significant differences in…
1 study
GRADE not reported
Adverse effects (narrative) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months)
SoF4. Adverse effects: single study narratively reported 4 participants (20%) in the bethanechol arm experienced adverse events (nausea, dizziness, blood pressure fall, cold perspiration or sporadic abdominal pain);…
1 study · 40 participants
Very low
Adverse effects of pain treatment · Adults undergoing orthodontic treatment
The review found no eligible studies for this question.
1 finding from 1 review