Question · asked by 1 review

Bowman-Birk inhibitor vs placebo or no treatment: Improvement of histological features (not improved)

Population
People with a diagnosis of oral leukoplakia
Intervention
Bowman-Birk inhibitor
Comparison
placebo or no treatment
Outcome
Improvement of histological features (not improved)

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Bowman-Birk inhibitor vs Placebo or no treatment
Improvement of histological features (not improved) · People with a diagnosis of oral leukoplakia
Interventions for treating oral leukoplakia to prevent oral cancer (2016) · Cochrane All outcomes
SoF 6, Histological changes: 'Not measured'. Effects text: data on histological changes from Armstrong 2013 were not available for analysis, but study authors reported no statistically significant differences in…1 studyGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for treating oral leukoplakia to prevent oral cancer
2016 · Cochrane All outcomes
2016-05Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.