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Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

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No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Intervention not reported

TXA given intravenously and intra‐articularly at a total dose of greater than 3 g pre‐incision, intraoperatively and postoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin or…
1 finding from 1 review

Intervention not reported

Time to hemostasis (seconds) · vascular surgery patients who undergo creation of an anastomosis

The intervention showed no clear difference in time to hemostasis (seconds) (low certainty).

1 finding from 1 review

Intervention not reported

Failure of hemostatic intervention ( · vascular surgery patients who undergo creation of an anastomosis

It is very uncertain whether the intervention changes failure of hemostatic intervention ( (very low certainty).

1 finding from 1 review

Intervention not reported

Intraoperative blood loss (mL) · vascular surgery patients who undergo creation of an anastomosis

The intervention showed no clear difference in intraoperative blood loss (mL) (low certainty).

1 finding from 1 review

Intervention not reported

Operating time (minutes) · vascular surgery patients who undergo creation of an anastomosis

The intervention showed no clear difference in operating time (minutes) (low certainty).

1 finding from 1 review

Intervention not reported

Death from bleeding complications (up to 30 days · vascular surgery patients who undergo creation of an anastomosis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Postoperative bleeding (up to 30 days · vascular surgery patients who undergo creation of an anastomosis

The intervention showed no clear difference in postoperative bleeding (up to 30 days (low certainty).

1 finding from 1 review

Intervention not reported

Unplanned return to the operating room (up to 30 days · vascular surgery patients who undergo creation of an anastomosis

The intervention showed no clear difference in unplanned return to the operating room (up to 30 days (low certainty).

1 finding from 1 review