Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,266 questions · 1,314 findings · 160 reviews · Headline outcomes only

No studies found 309 · 23.5%GRADE not reported 34 · 2.6%Very low 356 · 27.1%Low 393 · 29.9%Moderate 187 · 14.2%High 35 · 2.7%

Risk of postoperative infectious complications: anti‐integrin agents vs control

Intra‐abdominal infectious complications within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐integrin agents changes intra‐abdominal infectious complications within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐integrin agents vs control

Extra‐abdominal infections within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐integrin agents changes extra‐abdominal infections within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Corticosteroids vs control

Incisional infections and wound dehiscence within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: corticosteroids changes incisional infections and wound dehiscence within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Corticosteroids vs control

Intra‐abdominal infectious complications within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: corticosteroids changes intra‐abdominal infectious complications within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Corticosteroids vs control

Extra‐abdominal infections within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: corticosteroids changes extra‐abdominal infections within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

5‐ASA vs control

Infectious complications · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: 5‐ASA changes overall infectious complications within 30 days of surgery compared with control (very low certainty).

3 findings from 1 review

Vaginal misoprostol vs placebo

Opiate use (as a proxy measure for pain) for all participants on ITT (including those without confirmed AMI) · early fetal death (less than 24 weeks)

It is very uncertain whether vaginal misoprostol changes pain (opiate use) compared with placebo (very low certainty).

1 finding from 1 review