Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,085 questions · 1,232 findings · 66 reviews · All outcomes

No studies found 218 · 17.7%GRADE not reported 745 · 60.5%Very low 179 · 14.5%Low 65 · 5.3%Moderate 25 · 2%High 0 · 0%

Ozone applied to the carious lesion (10 or 40 seconds), with a fluoride reductant and oral hygiene/preventive advice vs No ozone, with a fluoride reductant and oral hygiene/preventive advice (as in the intervention group)

Adverse events · People of any age with caries (including demineralisation in non-cavitated carious lesions); the caries may affect any single tooth…
1 finding from 1 review
  • Ozone therapy for the treatment of dental caries 2004 · Cochrane All outcomes
    To 6 months
    Baysan 2003 stated that no adverse events were reported to 6 months; no information was provided by Abu-Naba'a 2003 or Abu-Naba'a 2003pilot.
    1 study
    GRADE not reported

Stabilisation splint (SS) vs acupuncture

Helkimo clinical dysfunction index · Patients with pain dysfunction syndrome (PDS) of all degrees of severity
1 finding from 1 review

Ozone applied to the carious lesion (10 or 40 seconds), with a fluoride reductant and oral hygiene/preventive advice vs No ozone, with a fluoride reductant and oral hygiene/preventive advice (as in the intervention group)

Patient satisfaction · People of any age with caries (including demineralisation in non-cavitated carious lesions); the caries may affect any single tooth…
1 finding from 1 review
  • Abu-Naba'a 2003 reported participants' state of anxiety, comparing ozone treatment with traditional dental interventions (injection, drilling, filling); because no participant was randomised between ozone and drilling…
    1 study
    GRADE not reported

Ozone applied to the carious lesion (10 or 40 seconds), with a fluoride reductant and oral hygiene/preventive advice vs No ozone, with a fluoride reductant and oral hygiene/preventive advice (as in the intervention group)

Further conventional dental treatment (filling and drilling) (binary yes/no) · People of any age with caries (including demineralisation in non-cavitated carious lesions); the caries may affect any single tooth…

The review found no eligible studies for this question.

1 finding from 1 review
  • Data were not provided by any study on the number of lesions requiring restorations to 6 months or later; no data on any further conventional treatment or other dental interventions.
    Studies not reported
    No studies found

Ozone applied to the carious lesion (10 or 40 seconds), with a fluoride reductant and oral hygiene/preventive advice vs No ozone, with a fluoride reductant and oral hygiene/preventive advice (as in the intervention group)

Costs · People of any age with caries (including demineralisation in non-cavitated carious lesions); the caries may affect any single tooth…

The review found no eligible studies for this question.

1 finding from 1 review

Ozone applied to the carious lesion (10 or 40 seconds), with a fluoride reductant and oral hygiene/preventive advice vs No ozone, with a fluoride reductant and oral hygiene/preventive advice (as in the intervention group)

Pain (assessed by the patient) · People of any age with caries (including demineralisation in non-cavitated carious lesions); the caries may affect any single tooth…

The review found no eligible studies for this question.

1 finding from 1 review

Ozone applied to the carious lesion (10 or 40 seconds), with a fluoride reductant and oral hygiene/preventive advice vs No ozone, with a fluoride reductant and oral hygiene/preventive advice (as in the intervention group)

Caries progression/regression (clinical severity index, log(e) ECM and log(e) DIAGNOdent scores) · People of any age with caries (including demineralisation in non-cavitated carious lesions); the caries may affect any single tooth…
1 finding from 1 review
  • Ozone therapy for the treatment of dental caries 2004 · Cochrane All outcomes
    6 and 12 months
    No consistent trend of benefit or harm following ozone was seen across the outcome measures in any of the three studies; analyses were conducted at the lesion level (not independent of the person), so data were not…
    3 studies · 137 participants
    GRADE not reported

Stabilisation splint (SS) vs Non-occluding splint

Pain (unpleasantness/intensity/palpation) · Patients with pain dysfunction syndrome (PDS) of all degrees of severity

Stabilisation splint (SS) showed no clear difference in pain (unpleasantness/intensity/palpation) compared with non-occluding splint; GRADE not reported.

1 finding from 1 review

Stabilisation splint (SS) vs Non-occluding splint

Movement (increase in maximal mouth opening) · Patients with pain dysfunction syndrome (PDS) of all degrees of severity

Stabilisation splint (SS) showed no clear difference in movement (increase in maximal mouth opening) compared with non-occluding splint; GRADE not reported.

1 finding from 1 review

Stabilisation splint (SS) vs relaxation

Pain (reduction in pain on palpation) · Patients with pain dysfunction syndrome (PDS) of all degrees of severity
1 finding from 1 review

Stabilisation splint (SS) vs Biofeedback/stress management

Helkimo clinical dysfunction index · Patients with pain dysfunction syndrome (PDS) of all degrees of severity

Stabilisation splint (SS) showed no clear difference in helkimo clinical dysfunction index compared with biofeedback/stress management; GRADE not reported.

1 finding from 1 review

Stabilisation splint (SS) vs Biofeedback/stress management

Muscle palpation pain (long term) · Patients with pain dysfunction syndrome (PDS) of all degrees of severity

Stabilisation splint (SS) showed no clear difference in pain (severity/muscle palpation) compared with biofeedback/stress management; GRADE not reported.

1 finding from 1 review

Stabilisation splint (SS) vs Jaw exercises

Pain (TMJ, muscle, on movement) · Patients with pain dysfunction syndrome (PDS) of all degrees of severity
1 finding from 1 review

Stabilisation splint (SS) vs relaxation

Maximal mouth opening (interincisal distance) · Patients with pain dysfunction syndrome (PDS) of all degrees of severity
1 finding from 1 review