Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,230 questions · 1,303 findings · 326 reviews · Headline outcomes only

No studies found 73 · 5.6%GRADE not reported 21 · 1.6%Very low 497 · 38.1%Low 403 · 30.9%Moderate 245 · 18.8%High 64 · 4.9%

Intervention not reported

Vespid Quality of Life Questionnaire ‐ end of treatment Scale from 0 to 7, where a higher score indicates less quality of life impairment. · adults and children with a previous allergic reaction to an insect sting
1 finding from 1 review

Intervention not reported

Pain (short term) WOMAC scale from 0 to 20 points (higher is worse pain). · Patients with peripheral joint osteoarthritis
1 finding from 1 review

Intervention not reported

Function (long term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with knee osteoarthritis
1 finding from 1 review

Intervention not reported

Function (short term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with peripheral joint osteoarthritis
1 finding from 1 review

Intervention not reported

Pain (long term) WOMAC scale from 0 to 20 points (higher is worse pain). · Patients with peripheral joint osteoarthritis
1 finding from 1 review

Intervention not reported

Function (long term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with peripheral joint osteoarthritis
1 finding from 1 review

Intervention not reported

Pain (short term) WOMAC scale from 0 to 20 points (higher is worse pain). · Patients with knee osteoarthritis
1 finding from 1 review

Intervention not reported

Function (short term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with knee osteoarthritis
1 finding from 1 review

Intervention not reported

Pain (long term) WOMAC scale from 0 to 20 points (higher is worse pain). · Patients with knee osteoarthritis
1 finding from 1 review

LOW DOSE (greater than or equal to 2‐<4 mg/day) vs ANY DOSE ‐ short term

Global state: No clinically important improvement ‐ global evaluation ‐ when compared with standard‐higher dose (greater than or equal to 6‐<10 mg/day) · patients with schizophrenia

LOW DOSE (greater than or equal to 2‐<4 mg/day) probably leads to higher global state: No clinically important improvement ‐ global… compared with ANY DOSE ‐ short term (moderate certainty).

1 finding from 1 review

LOW DOSE (greater than or equal to 2‐<4 mg/day) vs ANY DOSE ‐ short term

Adverse effects: 5a. Movement disorders ‐ specific symptoms ‐ EPS: unspecified ‐ versus standard‐higher dose (greater than or equal to 6‐<10 mg/day) · patients with schizophrenia

LOW DOSE (greater than or equal to 2‐<4 mg/day) showed no clear difference in adverse effects: 5a. Movement disorders ‐ specific symptoms ‐ EPS:… compared with ANY DOSE ‐ short term (moderate certainty).

1 finding from 1 review

STANDARD‐LOWER DOSE (greater than or equal to 4‐<6 mg/day) vs ANY DOSE ‐ short term

Leaving the study early: Any reasons ‐ when compared with standard‐higher dose (greater than or equal to 6‐<10 mg/day) · patients with schizophrenia

STANDARD‐LOWER DOSE (greater than or equal to 4‐<6 mg/day) showed no clear difference in leaving the study early: Any reasons ‐ when compared with… compared with ANY DOSE ‐ short term (moderate certainty).

1 finding from 1 review