Cochrane · systematic review · CD008838

Venom immunotherapy for preventing allergic reactions to insect stings

Boyle, RJ, Elremeli, M, Hockenhull, J, et al. · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library

SkinAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 3 · 75%High 1 · 25%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: adults and children with a previous allergic reaction to an insect sting
4 questions
OutcomeEffectEvidenceStatus / GRADE
Any systemic reaction to an insect sting
RR 0.1 [0.03, 0.28]7 studies · 206 participantsHigh
Large local reaction
RR 0.41 [0.24, 0.69]5 studies · 112 participantsModerate
Vespid Quality of Life Questionnaire ‐ end of treatment Scale from 0 to 7, where a higher score indicates less quality of life impairment.
no estimate extracted2 studies · 112 participantsModerate
Any systemic reaction to treatment
RR 8.16 [1.53, 43.46]6 studies · 285 participantsModerate