Intervention not reported
Adverse events ‐ recurrent fever · acute bacterial meningitis
The intervention probably leads to higher adverse events ‐ recurrent fever (moderate certainty).
1 finding from 1 review
Intervention not reported
Seizure frequency: Two out of five children had some improvement in seizure frequency. One child has unchanged seizure frequency and one child withdrew from the study and other had Infantile spasm. · children with intractable seizures
1 finding from 1 review
no estimate extracted
1 study · 3 participants
Low
Intervention not reported
Number of participants with exacerbations requiring systemic steroids · children with chronic asthma
The intervention showed no clear difference in number of participants with exacerbations requiring systemic steroids (moderate certainty).
1 finding from 1 review
Intervention not reported
Serious adverse events · children with chronic asthma
The intervention showed no clear difference in serious adverse events (moderate certainty).
1 finding from 1 review
Intervention not reported
Total number of withdrawals · children with chronic asthma
The intervention showed no clear difference in total number of withdrawals (moderate certainty).
1 finding from 1 review
Intervention not reported
Change in FEV1 (L) at endpoint · children with chronic asthma
1 finding from 1 review
Intervention not reported
Change in morning PEF (L/min) at endpoint · children with chronic asthma
1 finding from 1 review
Intervention not reported
Total number of adverse events · children with chronic asthma
The intervention showed no clear difference in total number of adverse events (high certainty).
1 finding from 1 review
Intervention not reported
Number of participants with exacerbations requiring hospitalisation · children with chronic asthma
The intervention showed no clear difference in number of participants with exacerbations requiring hospitalisation (moderate certainty).
1 finding from 1 review
Intervention not reported
Serious adverse events · children with chronic asthma
The intervention showed no clear difference in serious adverse events (moderate certainty).
1 finding from 1 review
Intervention not reported
Total number of withdrawals · children with chronic asthma
The intervention may leads to lower total number of withdrawals (low certainty).
1 finding from 1 review
Intervention not reported
Change in FEV1 (L) at endpoint · children with chronic asthma
1 finding from 1 review
Intervention not reported
Change in morning PEF (L/min) at endpoint · children with chronic asthma
1 finding from 1 review
Intervention not reported
Total number of adverse events · children with chronic asthma
The intervention showed no clear difference in total number of adverse events (moderate certainty).
1 finding from 1 review
Intervention not reported
Number of participants with exacerbations requiring systemic steroids · children with chronic asthma
The intervention showed no clear difference in number of participants with exacerbations requiring systemic steroids (moderate certainty).
1 finding from 1 review
Intervention not reported
Number of participants with exacerbations requiring hospitalisation · children with chronic asthma
The intervention showed no clear difference in number of participants with exacerbations requiring hospitalisation (moderate certainty).
1 finding from 1 review
Death at hospital discharge · neonates with clinical and microbiological features of bacterial meningitis
It is very uncertain whether adjunctive steroid changes all‐cause death until hospital discharge compared with placebo (very low certainty).
1 finding from 1 review
Developmental delay at ≥ 18 months · neonates with clinical and microbiological features of bacterial meningitis
Adjunctive steroid showed no clear difference in number of participants with developmental delay compared with placebo (low certainty).
1 finding from 1 review
Hearing loss · neonates with clinical and microbiological features of bacterial meningitis
Adjunctive steroid showed no clear difference in hearing loss at 2 years of age compared with placebo (low certainty).
2 findings from 1 review
Intervention not reported
Pain at 1 week Scale from: 0 to 10 · adult patients with cancer‐related pain
1 finding from 1 review