Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,438 questions · 1,463 findings · 125 reviews · Anaesthesia

No studies found 197 · 13.5%GRADE not reported 203 · 13.9%Very low 307 · 21%Low 441 · 30.1%Moderate 245 · 16.7%High 70 · 4.8%

Intervention not reported

Number of participants receiving blood transfusion: antifibrinolytics vs placebo · children undergoing surgery for scoliosis

It is very uncertain whether the intervention changes number of participants receiving blood transfusion:… (very low certainty).

1 finding from 1 review

Intervention not reported

Number of participants receiving blood transfusion: aminocaproic acid vs placebo · children undergoing surgery for scoliosis

It is very uncertain whether the intervention changes number of participants receiving blood transfusion: aminocaproic… (very low certainty).

1 finding from 1 review

Intervention not reported

Number of participants receiving blood transfusion: aprotinin vs placebo · children undergoing surgery for scoliosis

It is very uncertain whether the intervention changes number of participants receiving blood transfusion: aprotinin vs… (very low certainty).

1 finding from 1 review

Intervention not reported

Number of participants receiving blood transfusion: tranexamic acid vs placebo · children undergoing surgery for scoliosis

It is very uncertain whether the intervention changes number of participants receiving blood transfusion: tranexamic acid… (very low certainty).

1 finding from 1 review

Anaesthesia depth monitors (BIS and M‐entropy) vs standard monitoring

Awareness Postoperative interview · patients with prevention of recall of events during surgery

Anaesthesia depth monitors (BIS and M‐entropy) showed no clear difference in awareness Postoperative interview compared with standard clinical and electronic monitoring (low certainty).

1 finding from 1 review

Intervention not reported

Awareness Postoperative interview1 · patients with decreasing recall of events during surgery

It is very uncertain whether the intervention changes awareness Postoperative interview1 (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse effects of intraoperative wakefulness and/or postoperative awareness (i.e. post‐traumatic stress syndrome, myocardial infarction, cardiac arrest, etc.) · patients with decreasing recall of events during surgery

The review found no eligible studies for this question.

1 finding from 1 review

Anaesthesia depth monitors (BIS and M‐entropy) vs standard monitoring

Adverse effects of intraoperative wakefulness and/or postoperative awareness (i.e. post‐traumatic stress syndrome, myocardial infarction, cardiac arrest, etc.) · patients with prevention of recall of events during surgery

The review found no eligible studies for this question.

1 finding from 1 review

Anaesthesia depth monitors (BIS) vs standard monitoring

Awareness: definite and possible Postoperative interview · patients with prevention of recall of events during surgery

Anaesthesia depth monitors (BIS) showed no clear difference in awareness: definite and possible Postoperative interview compared with standard clinical and electronic monitoring (low certainty).

1 finding from 1 review

Anaesthesia depth monitors (BIS) vs standard monitoring

Awareness: definite Postoperative interview · patients with prevention of recall of events during surgery

Anaesthesia depth monitors (BIS) showed no clear difference in awareness: definite Postoperative interview compared with standard clinical and electronic monitoring (low certainty).

1 finding from 1 review

Anaesthesia depth monitors (BIS) vs standard monitoring

Adverse effects of intraoperative wakefulness and/or postoperative awareness (i.e. post‐traumatic stress syndrome, myocardial infarction, cardiac arrest, etc.) · patients with prevention of recall of events during surgery

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Intraoperative Wakefulness Postoperative Interview · patients with prevention of recall of events during surgery

The intervention may leads to lower intraoperative Wakefulness Postoperative Interview (low certainty).

1 finding from 1 review

Intervention not reported

Adverse effects of intraoperative wakefulness and/or postoperative awareness (i.e. post‐traumatic stress syndrome, myocardial infarction, cardiac arrest, etc.) · patients with prevention of recall of events during surgery

The review found no eligible studies for this question.

1 finding from 1 review

Thiopentone and ketamine vs benzodiazepines

Awareness Postoperative interview · patients with prevention of recall of events during surgery

It is very uncertain whether thiopentone and ketamine changes awareness Postoperative interview compared with benzodiazepines (diazepam, midazolam, lorazepam) (very low certainty).

1 finding from 1 review

Thiopentone and ketamine vs benzodiazepines

Adverse effects of intraoperative wakefulness and/or postoperative awareness (i.e. post‐traumatic stress syndrome, myocardial infarction, cardiac arrest, etc.) · patients with prevention of recall of events during surgery

The review found no eligible studies for this question.

1 finding from 1 review