Cardiovascular mortality · patients with diabetes mellitus
Tight glycaemic control showed no clear difference in cardiovascular mortality 4.4 years compared with non‐tight control (low certainty).
1 finding from 1 review
Non‐fatal MI · patients with diabetes mellitus
Tight glycaemic control probably leads to lower non‐fatal myocardial infarction 5.6 years compared with non‐tight control (moderate certainty).
1 finding from 1 review
Onset microalbuminuria 5.4 years · patients with diabetes mellitus
Tight glycaemic control probably leads to lower onset microalbuminuria 5.4 years compared with non‐tight control (moderate certainty).
1 finding from 1 review
Progression of microalbuminuria 5.8 years · patients with diabetes mellitus
Tight glycaemic control probably leads to lower progression of microalbuminuria 5.8 years compared with non‐tight control (moderate certainty).
1 finding from 1 review
Number of participants with symptomatic UTI · people with neuropathic bladder
It is very uncertain whether intravesical bacterial interference changes symptomatic UTI compared with placebo (very low certainty).
1 finding from 1 review
Intervention not reported
Serum creatinine: day 1 · patients undergoing a surgical intervention that induces kidney injury
1 finding from 1 review
no estimate extracted
Studies not reported
High
Intervention not reported
Serum creatinine: day 2 · patients undergoing a surgical intervention that induces kidney injury
1 finding from 1 review
no estimate extracted
Studies not reported
High
Intervention not reported
Serum creatinine: day 3 · patients undergoing a surgical intervention that induces kidney injury
1 finding from 1 review
no estimate extracted
Studies not reported
High
Intervention not reported
Adverse events related to RIPC · patients undergoing a surgical intervention that induces kidney injury
The intervention showed no clear difference in adverse events related to RIPC (high certainty).
1 finding from 1 review
RR 3.47 [0.55, 21.76]
Studies not reported
High
Intervention not reported
Need for dialysis · patients undergoing a surgical intervention that induces kidney injury
The intervention showed no clear difference in need for dialysis (moderate certainty).
1 finding from 1 review
RR 0.85 [0.37, 1.94]
Studies not reported
Moderate
Intervention not reported
Acute kidney injury defined by AKIN · patients undergoing a surgical intervention that induces kidney injury
The intervention showed no clear difference in acute kidney injury defined by AKIN (high certainty).
1 finding from 1 review
RR 0.76 [0.57, 1]
Studies not reported
High
Intervention not reported
Mortality · patients undergoing a surgical intervention that induces kidney injury
The intervention showed no clear difference in mortality (high certainty).
1 finding from 1 review
RR 0.86 [0.54, 1.37]
Studies not reported
High
All strokes and systemic embolic events · atrial fibrillation patients with CKD
Direct oral anticoagulants (DOAC) showed no clear difference in all strokes and systemic embolic events compared with warfarin (moderate certainty).
1 finding from 1 review
Major bleeding · atrial fibrillation patients with CKD
Direct oral anticoagulants (DOAC) showed no clear difference in major bleeding compared with warfarin (low certainty).
1 finding from 1 review
Myocardial infarction · atrial fibrillation patients with CKD
Direct oral anticoagulants (DOAC) showed no clear difference in myocardial infarction compared with warfarin; GRADE not reported.
1 finding from 1 review
Minor bleeding · atrial fibrillation patients with CKD
Direct oral anticoagulants (DOAC) showed no clear difference in minor bleeding compared with warfarin (low certainty).
1 finding from 1 review
Gastrointestinal bleeding · atrial fibrillation patients with CKD
Direct oral anticoagulants (DOAC) showed no clear difference in gastrointestinal bleeding compared with warfarin (moderate certainty).
1 finding from 1 review
Intracranial haemorrhage · atrial fibrillation patients with CKD
Direct oral anticoagulants (DOAC) probably leads to lower intracranial haemorrhage compared with warfarin (moderate certainty).
1 finding from 1 review
All‐cause mortality · atrial fibrillation patients with CKD
Direct oral anticoagulants (DOAC) showed no clear difference in all‐cause mortality compared with warfarin (moderate certainty).
1 finding from 1 review
Access thrombosis/vascular complication · people receiving haemodialysis to treat kidney failure and using a functioning AV access for haemodialysis.
Scheduled surveillance showed no clear difference in risk of access thrombosis compared with clinical monitoring alone (moderate certainty).
1 finding from 1 review