Findings

What do systematic reviews say?

4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only

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No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%

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Intervention not reported

Anthropometric outcomes: total MUAC gain Defined as MUAC at discharge − MUAC on admission among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 532 participants
Very low

Intervention not reported

Anthropometric outcomes: MUAC gain per day Defined as (discharge MUAC − admission MUAC)/days in treatment among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 531 participants
Very low

Intervention not reported

Anthropometric outcomes: total weight gain (g/kg) Defined as (weight at discharge − weight on admission)/weight on admission among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 517 participants
Very low

Intervention not reported

Anthropometric outcomes: mean weight gain per day (g/kg/d) Defined as ((discharge weight − admission weight)/admission weight)/days in treatment (Wilunda 2021)e · children aged > 6 months and < 5 years with wasting

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 343 participants
Very low

Intervention not reported

Anthropometric outcomes: median weight gain per day (g/kg/d) Defined as ((discharge weight − admission weight)/weight on admission)/days on treatment among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 517 participants
Very low

Intervention not reported

Anthropometric outcomes: number of children with normal or underweight WHZ on discharge Defined as WHZ > −2 (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with normal or… (low certainty).

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
RR 0.94 [0.28, 3.18]
1 study · 789 participants
Low

Intervention not reported

Anthropometric outcomes: number of children with WHZ in moderate wasting range on discharge Defined as WHZ between −3 and −2 (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with WHZ in moderate… (moderate certainty).

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
RR 1.09 [0.87, 1.36]
1 study · 789 participants
Moderate

Intervention not reported

Anthropometric outcomes: number of children with WHZ in severe wasting range on discharge Defined as WHZ < −3: Hussain 2021 · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with WHZ in severe… (moderate certainty).

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
RR 1.23 [0.75, 2.04]
1 study · 789 participants
Moderate

Intervention not reported

Anthropometric outcomes: number of children with MUAC ≥ 115 mm on discharge (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with MUAC ≥ 115 mm on… (moderate certainty).

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
RR 0.99 [0.93, 1.06]
1 study · 789 participants
Moderate

Intervention not reported

Anthropometric outcomes: weight gain per day (g/kg/day) Calculated as ((discharge weight − admission weight)/weight on admission)/days in treatment among recovered children (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

1 finding from 1 review

Lay health workers in primary and community health care for maternal and child health: identification and treatment of… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 571 participants
High

Intervention not reported

Potency/bioactivity parameters of human insulin · healthy physicians

The review found no eligible studies for this question.

1 finding from 1 review

Thermal stability and storage of human insulin 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings. Peer reviewer training vs standard journal practice or no training

Bibliometric scores · peer reviewers

The review found no eligible studies for this question.

1 finding from 1 review

Reviewer training for improving grant and journal peer review 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Walking speedg ‐ overall analysis Measured using metres/second (m/s) and metres/minute (m/min). A higher score indicates faster walking. · adults following hip fracture surgery

The intervention leads to higher walking speedg ‐ overall analysis Measured using metres/second (m/s)… (high certainty).

1 finding from 1 review

Interventions for improving mobility after hip fracture surgery in adults 2022 · Cochrane Headline outcomes only
SMD 0.16 [0.04, 0.29]
14 studies · 1067 participants
High

Intervention not reported

Walking speedg ‐ overall analysis Measured using metres/second (m/s) and metres/minute (m/min). A higher score indicates faster walking. · adults following hip fracture surgery

The intervention showed no clear difference in walking speedg ‐ overall analysis Measured using metres/second (m/s)… (moderate certainty).

1 finding from 1 review

Interventions for improving mobility after hip fracture surgery in adults 2022 · Cochrane Headline outcomes only
SMD 0.16
6 studies · 360 participants
Moderate

Interventions (ibuprofen, tolfenamic acid, aspirin, tranexamic acid) vs placebo or active comparators (paracetamol, tranexamic acid)

Menstrual blood loss: mean loss

Interventions (ibuprofen, tolfenamic acid, aspirin, tranexamic acid) showed no clear difference in menstrual blood loss (alkaline hematin method) compared with placebo or active comparators (paracetamol, tranexamic acid); GRADE not reported.

2 findings from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
MD 14.11
Studies not reported
GRADE not reported
Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
MD 0.3
Studies not reported
GRADE not reported

Interventions (ibuprofen, tolfenamic acid, aspirin, tranexamic acid) vs placebo or active comparators (paracetamol, tranexamic acid)

Menstrual blood loss % occurrence of heavy menstrual bleeding (alkaline hematin method)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Interventions (vitamin B1, mefenamic acid, tranexamic acid) vs placebo or active comparators (desmopressin, sodium diclofenac, flavonoids)

Menstrual blood loss: mean loss

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Very low

Corticosteroids vs no corticosteroid use

Time for laboratory parameters to normalise: CRP, ESR (days) Duration: N/A · children diagnosed with Kawasaki disease

1 finding from 1 review

Corticosteroids for the treatment of Kawasaki disease in children 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 178 participants
Moderate

Summary of findings for cholinesterase inhibitors vs placebo

Quality of life immediately after the intervention · people with Parkinson's disease

1 finding from 1 review

Interventions for preventing falls in Parkinson's disease 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 121 participants
Very low

Laser therapy plus other treatment vs other treatment

Scar severity ‐ Helium‐Neon (He‐Ne) laser plus decamethyltetrasiloxane, polydimethylsiloxane and cyclopentasiloxane cream versus decamethyltetrasiloxane, polydimethylsiloxane and cyclopentasiloxane cream ‐ Vancouver Scar scale (VSS) (higher scores... · participants with hypertrophic and keloid scars

1 finding from 1 review

Laser therapy for treating hypertrophic and keloid scars 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low