Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,454 questions · 3,562 findings · 816 reviews · Headline outcomes only

No studies found 538 · 15.1%GRADE not reported 239 · 6.7%Very low 933 · 26.2%Low 1,041 · 29.2%Moderate 612 · 17.2%High 199 · 5.6%

Point‐of‐care biomarkers (procalcitonin) for infection vs usual care

Clinical recovery · people with acute respiratory infections

The review found no eligible studies for this question.

2 findings from 1 review

Point‐of‐care biomarkers (C‐reactive protein) for infection vs usual care

Clinical recovery · people with acute respiratory infections
2 findings from 1 review

Full or partial opioid agonist maintenance vs placebo, detoxification only or psychological treatment (buprenorphine maintenance compared to taper or treatment

Days of unsanctioned opioid use · pharmaceutical opioid dependent people

Full or partial opioid agonist maintenance showed no clear difference in days of unsanctioned opioid use (as number of days/30 or days/7) compared with placebo, detoxification only or psychological treatment… (low certainty).

1 finding from 1 review

Intervention not reported

Mortality (within 30 days or 'in‐hospital') · adults with any pancreatic diagnosis leading to an indication for elective (classical, pylorus‐preserving, pylorus‐resecting) partial…

The intervention showed no clear difference in mortality (within 30 days or 'in‐hospital') (high certainty).

1 finding from 1 review

Intervention not reported

Length of postoperative hospital stay (days) · adults with any pancreatic diagnosis leading to an indication for elective (classical, pylorus‐preserving, pylorus‐resecting) partial…

The intervention showed no clear difference in length of postoperative hospital stay (days) (low certainty).

1 finding from 1 review

Immediate vs delayed postpartum insertion of contraceptive implants

Adverse effect: mean days of prolonged vaginal bleeding within 6 weeks postpartum · postpartum people who desire a contraceptive implant for contraception

Immediate may leads to higher adverse effect: mean days of prolonged vaginal bleeding within 6… compared with delayed postpartum insertion of contraceptive implants (low certainty).

1 finding from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Drug holidays · solid organ transplant recipients

Interventions for increasing immunosuppressant medication adherence showed no clear difference in drug holidays compared with standard care (low certainty).

1 finding from 1 review