Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,163 questions · 1,209 findings · 133 reviews · Headline outcomes only

No studies found 176 · 14.6%GRADE not reported 47 · 3.9%Very low 241 · 19.9%Low 323 · 26.7%Moderate 315 · 26.1%High 107 · 8.9%

Intervention not reported

Mortality · acute bacterial meningitis

The intervention showed no clear difference in mortality (moderate certainty).

1 finding from 1 review

Intervention not reported

Severe hearing loss · acute bacterial meningitis

The intervention leads to lower severe hearing loss (high certainty).

1 finding from 1 review

Intervention not reported

Any hearing loss · acute bacterial meningitis

The intervention leads to lower any hearing loss (high certainty).

1 finding from 1 review

Intervention not reported

Short‐term neurological sequelae · acute bacterial meningitis

The intervention showed no clear difference in short‐term neurological sequelae (high certainty).

1 finding from 1 review