Intervention not reported
Respiratory depression · children (aged < 18 years) with acute severe pain
1 finding from 1 review
Intervention not reported
Hypotension · children (aged < 18 years) with acute severe pain
1 finding from 1 review
Intervention not reported
Decreased level of consciousness · children (aged < 18 years) with acute severe pain
1 finding from 1 review
Intervention not reported
Intolerance to analgesia · children (aged < 18 years) with acute severe pain
1 finding from 1 review
Intervention not reported
Use of ED "rescue" analgesia · children (aged < 18 years) with acute severe pain
1 finding from 1 review
Bayley Scale PDI within 30 days of commencement of therapy · children less than 3 years of age with iron deficiency anaemia
1 finding from 1 review
Bayley Scale MDI within 30 days of commencement of therapy · children less than 3 years of age with iron deficiency anaemia
1 finding from 1 review
Bayley Scale PDI more than 30 days of commencement of therapy · children less than 3 years of age with iron deficiency anaemia
1 finding from 1 review
Bayley Scale MDI more than 30 days of commencement of therapy · children less than 3 years of age with iron deficiency anaemia
1 finding from 1 review
Denver Developmental Screening Test more than 30 days of commencement of therapy · children less than 3 years of age with iron deficiency anaemia
1 finding from 1 review
Intervention not reported
Number reoffendingadministrative data · Offenders aged 7 to 21 years
It is very uncertain whether the intervention changes number reoffendingadministrative data (very low certainty).
1 finding from 1 review
Intervention not reported
Post‐intervention monthly offending rate (any offence)administrative data · Offenders aged 7 to 21 years
1 finding from 1 review
Intervention not reported
Remorseparticipant interviews · Offenders aged 7 to 21 years
It is very uncertain whether the intervention changes remorseparticipant interviews (very low certainty).
1 finding from 1 review
Intervention not reported
Recognition of wrongdoingparticipant interviews · Offenders aged 7 to 21 years
It is very uncertain whether the intervention changes recognition of wrongdoingparticipant interviews (very low certainty).
1 finding from 1 review
Intervention not reported
Self‐perceptionparticipant interviews · Offenders aged 7 to 21 years
It is very uncertain whether the intervention changes self‐perceptionparticipant interviews (very low certainty).
1 finding from 1 review
Intervention not reported
Young offender satisfactionparticipant interviews · Offenders aged 7 to 21 years
It is very uncertain whether the intervention changes young offender satisfactionparticipant interviews (very low certainty).
1 finding from 1 review
Intervention not reported
Victim/key stakeholder satisfaction with overall processparticipant interviews · Offenders aged 7 to 21 years
It is very uncertain whether the intervention changes victim/key stakeholder satisfaction with overall processparticipant… (very low certainty).
1 finding from 1 review
Plaque · Dentate adults aged 16 years or older (excluding orthodontic patients and those with severe periodontal disease)
It is very uncertain whether flossing plus toothbrushing (self-performed; manual or automated… changes plaque (Turesky-modified Quigley-Hein/other plaque indices; SMD) compared with toothbrushing alone (with or without a negative-control/placebo rinse) (very low certainty).
3 findings from 1 review
SMD -0.23 [-0.52, 0.06]
5 studies · 416 participants
Very low
SMD -0.06 [-0.23, 0.12]
3 studies · 487 participants
GRADE not reported
SMD -0.20 [-0.36, -0.04]
5 studies · 594 participants
GRADE not reported
Side effects · Dentate adults aged 16 years or older (excluding orthodontic patients and those with severe periodontal disease)
1 finding from 1 review
Not estimable (5 studies). Adverse effects were assessed in five studies, but they used different outcome measures, so meta-analysis was not appropriate. The main harm identified was soft-tissue trauma to the gingival…
5 studies
GRADE not reported
Gingivitis · Dentate adults aged 16 years or older (excluding orthodontic patients and those with severe periodontal disease)
Flossing plus toothbrushing (self-performed; manual or automated… led to lower gingivitis (Gingival Index, 0-3 scale; SMD) compared with toothbrushing alone (with or without a negative-control/placebo rinse); GRADE not reported.
3 findings from 1 review
SMD -0.41 [-0.68, -0.14]
6 studies · 656 participants
GRADE not reported
SMD -0.36 [-0.66, -0.05]
7 studies · 489 participants
Very low
SMD -0.72 [-1.09, -0.35]
4 studies · 564 participants
GRADE not reported