Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,908 questions · 3,101 findings · 509 reviews

No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Metformin vs diet and exercise or another antidiabetic drug

Intensive diet plus exercise · people at increased risk for developing type 2 diabetes
4 findings from 1 review
Show 1 more finding

Metformin vs diet and exercise or another antidiabetic drug

Intensive diet plus exercise Diagnostic criteria: 1 trial applied the WHO 1985 criteria (FPG < 7.8 mmol/L and 2‐hour glucose ≥ 7.8 mmol/L and < 11.1 mmol/L) (Fang 2004) · people at increased risk for developing type 2 diabetes

Summary of findings table for metformin showed no clear difference in intensive diet plus exercise Diagnostic criteria: 1 trial applied… compared with diet and exercise or another antidiabetic drug (moderate certainty).

1 finding from 1 review

Continuous glucose monitoring system vs intermittent glucose monitoring

Hypertensive disorders of pregnancy · women with pre‐existing diabetes

Continuous glucose monitoring may leads to lower hypertensive disorders of pregnancy (including pre‐eclampsia,… compared with intermittent glucose monitoring (low certainty).

1 finding from 1 review

Self‐monitoring at home vs hospitalisation

Hypertensive disorders of pregnancy · women with pre‐existing diabetes

It is very uncertain whether self‐monitoring at home changes hypertensive disorders of pregnancy (including pre‐eclampsia,… compared with hospitalisation (very low certainty).

1 finding from 1 review

Intervention not reported

Diarrhoea prevalence Controlled cross‐sectional studies: Health Extension Package intervention (Ethiopia) · adults and children

It is very uncertain whether the intervention changes diarrhoea prevalence Controlled cross‐sectional studies: Health… (very low certainty).

1 finding from 1 review

Low dialysate [Na+] (< 138 mM) vs neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (> 140 mM)

Intradialytic hypotension · chronic HD

Low dialysate [Na+] (< 138 mM) probably leads to higher intradialytic hypotension compared with neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (>… (moderate certainty).

1 finding from 1 review