Interventions to increase adherence showed no clear difference in short‐term abstinence from smoking (< 6 months) compared with standard care (low certainty).
Interventions to increase adherence showed no clear difference in long‐term abstinence from smoking (≥ 6 months) compared with standard care (low certainty).
Tamoxifen probably leads to lower overall breast cancer incidence compared with placebo (moderate certainty).
Tamoxifen probably leads to higher severe toxicity compared with placebo (moderate certainty).
Aromatase inhibitors leads to lower overall breast cancer incidence compared with placebo (high certainty).
Aromatase inhibitors leads to higher severe toxicity compared with placebo (high certainty).
Aromatase inhibitors may leads to lower overall breast cancer incidence compared with tamoxifen (indirect comparison)a (low certainty).
It is very uncertain whether CHOLINERGIC DRUGS changes tardive dyskinesia: No clinically important improvement compared with PLACEBO (very low certainty).
CHOLINERGIC DRUGS showed no clear difference in tardive dyskinesia: Deterioration compared with PLACEBO (low certainty).
It is very uncertain whether CHOLINERGIC DRUGS changes mental state: Deterioration compared with PLACEBO (very low certainty).
It is very uncertain whether CHOLINERGIC DRUGS changes adverse effects: Any adverse events compared with PLACEBO (very low certainty).
It is very uncertain whether CHOLINERGIC DRUGS changes acceptability of treatment: Leaving the study early compared with PLACEBO (very low certainty).
The review found no eligible studies for this question.
Clomiphene citrate or letrozole with or without gonadotropins (with… showed no clear difference in live birth per woman compared with gonadotropins (with GnRH agonists or midcycle antagonist) (low certainty).
Clomiphene citrate or letrozole with or without gonadotropins (with… may leads to lower ovarian hyperstimulation syndrome per woman compared with gonadotropins (with GnRH agonists or midcycle antagonist) (low certainty).
Clomiphene citrate or letrozole with or without gonadotropins (with… showed no clear difference in clinical pregnancy rate per woman compared with gonadotropins (with GnRH agonists or midcycle antagonist) (moderate certainty).
Clomiphene citrate or letrozole with or without gonadotropins (with… may leads to higher cancellation rate per woman compared with gonadotropins (with GnRH agonists or midcycle antagonist) (low certainty).