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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Population

Intervention or exposure

Comparison

Outcome

Any field or review title

Field or topic

Source

Review versions

210 questions in 21 reviews · Lung Cancer

current versions

No studies 15 · 7.1%Ungraded 2 · 1%Very low 15 · 7.1%Low 66 · 31.4%Moderate 50 · 23.8%High 62 · 29.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Question	Effect	Evidence	Status / GRADE
Annual low‐dose CT screening vs annual chest x‐ray Lung cancer mortality · Patients with lung cancer Screening for lung cancer (2013) · Cochrane	RR 0.8 [0.7, 0.92]	1 study · 53454 participants	High
Annual low‐dose CT screening vs annual chest x‐ray All‐cause mortality · Patients with lung cancer Screening for lung cancer (2013) · Cochrane	RR 0.94 [0.88, 1]	1 study · 53454 participants	High
Lung cancer screening with chest radiography +/‐ sputum cytology vs less intense screening Lung cancer mortality ‐ Annual chest x‐ray plus 4‐monthly cytology versus annual x‐ray alone · Patients with lung cancer Screening for lung cancer (2013) · Cochrane	RR 0.88 [0.74, 1.03]	2 studies · 20427 participants	High
Lung cancer screening with chest radiography +/‐ sputum cytology vs less intense screening All‐cause mortality ‐ More frequent chest x‐ray screening versus less frequent screening · Patients with lung cancer Screening for lung cancer (2013) · Cochrane	RR 1.01 [0.94, 1.08]	4 studies · 170149 participants	Low
Lung cancer screening with chest radiography +/‐ sputum cytology vs less intense screening All‐cause mortality ‐ Annual chest x‐ray plus 4‐monthly cytology versus annual x‐ray alone · Patients with lung cancer Screening for lung cancer (2013) · Cochrane	RR 1.03 [0.91, 1.15]	1 study · 10040 participants	High
Lung cancer screening with chest radiography +/‐ sputum cytology vs less intense screening Lung cancer 5‐year survival ‐ More frequent chest x‐ray screening versus less frequent screening · Patients with lung cancer Screening for lung cancer (2013) · Cochrane	RR 0.91 [0.84, 0.99]	4 studies · 1775 participants	Low
Lung cancer screening with chest radiography +/‐ sputum cytology vs less intense screening Lung cancer 5‐year survival ‐ Annual chest x‐ray plus 4‐monthly cytology versus annual x‐ray alone · Patients with lung cancer Screening for lung cancer (2013) · Cochrane	RR 0.83 [0.75, 0.92]	1 study · 837 participants	Moderate
Annual chest x‐ray screening vs usual care (no regular screening) Lung cancer mortality at 6 years of · Patients with lung cancer Screening for lung cancer (2013) · Cochrane	RR 0.91 [0.81, 1.03]	1 study · 154901 participants	High
Annual chest x‐ray screening vs usual care (no regular screening) Lung cancer mortality at 13 years of · Patients with lung cancer Screening for lung cancer (2013) · Cochrane	RR 0.99 [0.91, 1.07]	1 study · 154901 participants	High
Annual chest x‐ray screening vs usual care (no regular screening) Deaths from all causes (excluding deaths from PLCO cancers) · Patients with lung cancer Screening for lung cancer (2013) · Cochrane	RR 0.98 [0.96, 1.01]	1 study · 154901 participants	High