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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

775 questions in 58 reviews · Bone, Joint and Muscle Trauma

current versions
No studies 166 · 21.4%Ungraded 24 · 3.1%Very low 356 · 45.9%Low 162 · 20.9%Moderate 47 · 6.1%High 20 · 2.6%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Uncemented modern unipolar hemiarthroplasty (4 RCTs; 891 participants)a · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
Surgical interventions for treating intracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 1.16 [0.93, 1.45]4 studies · 891 participantsVery low
Intervention NR
Total hip arthroplasty (single articulation) (2 RCTs; 225 participants)a · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
Surgical interventions for treating intracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 1.62 [1.13, 2.32]2 studies · 225 participantsVery low
Intervention NR
Dual‐mobility total hip arthroplasty (No direct evidence, indirect evidence only) · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
Surgical interventions for treating intracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 1.07 [0.37, 3.14]NRVery low
Intervention NR
Total studies: 56 Total participants: 8407 · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
no estimate extracted56 participantsUngraded
Intervention NR
Dynamic fixed angle plate · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Total studies: 55 Total participants: 9296 · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
no estimate extracted55 participantsUngraded
Intervention NR
Static fixed angle plate (4 studies; 622 participants)a · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 2.48 [1.36, 4.5]4 studies · 622 participantsVery low
Intervention NR
Long cephalomedullary nail (2 studies; 400 participants)a · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 1.58 [0.55, 4.56]2 studies · 400 participantsVery low
Intervention NR
Short cephalomedullary nail (34 studies; 6437 participants)a · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 1.12 [0.8, 1.56]34 studies · 6437 participantsVery low
Intervention NR
Condylocephalic nail (7 studies; 996 participants)a · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 3.33 [1.95, 5.68]7 studies · 996 participantsVery low
Intervention NR
External fixation (1 studies; 100 participants)a · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 0.09 [0, 1.87]1 study · 100 participantsLow
Intervention NR
Hemiarthroplasty (No direct evidence, indirect evidence only) · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 0.37 [0.01, 10.26]NRVery low
Intervention NR
Dynamic fixed angle plate · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Static fixed angle plate (5 studies; 847 participants)a · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 1.02 [0.77, 1.36]5 studies · 847 participantsVery low
Intervention NR
Long cephalomedullary nail (2 studies; 400 participants)a · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 1.27 [0.89, 1.81]2 studies · 400 participantsVery low
Intervention NR
Short cephalomedullary nail (33 studies; 5380 participants)a · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 0.97 [0.87, 1.07]33 studies · 5380 participantsVery low
Intervention NR
Condylocephalic nail (6 studies; 847 participants)a · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 0.93 [0.74, 1.16]6 studies · 847 participantsVery low
Intervention NR
External fixation (1 study; 100 participants)a · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 0.75 [0.36, 1.57]1 study · 100 participantsLow
Intervention NR
Hemiarthroplasty (No direct evidence, indirect evidence only) · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 1.36 [0.73, 2.54]NRVery low
Intervention NR
Non‐operative treatment (1 study; 106 participants)a · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 1 [0.53, 1.87]1 study · 106 participantsLow
Intervention NR
Total hip arthroplasty (1 study; 156 participants)a · older adults (> 60 years of age) with extracapsular hip fractures
Surgical interventions for treating extracapsular hip fractures in older adults: a network meta‐analysis (2022) · Cochrane
RR 0.69 [0.12, 4.03]1 study · 156 participantsLow
Cemented vs uncemented hemiarthroplasty
Activities in daily living, early (within 4 months): using GARS (range from 18 to 72), a social dependency scale (range of scores 1 to 9); lower values in these scales indicate more independence. Also using OARS‐IADL (range from 0 to 14) and a 5‐p... · adults with displaced and undisplaced hip fractures; included studies were for intracapsular fractures, except for one…
Arthroplasties for hip fracture in adults (2022) · Cochrane
no estimate extracted4 studies · 1275 participantsModerate
Bipolar hemiarthroplasty vs unipolar hemiarthroplasty
Early delirium · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
RR 0.48 [0.09, 2.58]1 study · 261 participantsVery low
Bipolar hemiarthroplasty vs unipolar hemiarthroplasty
Functional status, early (within 4 months) · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
no estimate extractedNRNo studies
Bipolar hemiarthroplasty vs unipolar hemiarthroplasty
HRQoL, early (within 4 months): using EQ‐5D (range 0 to 1); higher values indicate better quality of life · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
no estimate extracted1 study · 115 participantsVery low
Bipolar hemiarthroplasty vs unipolar hemiarthroplasty
Mobility, early (within 4 months) · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
no estimate extractedNRNo studies
Bipolar hemiarthroplasty vs unipolar hemiarthroplasty
Mortality, early (within 4 months) · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
RR 0.94 [0.54, 1.64]4 studies · 573 participantsLow
Bipolar hemiarthroplasty vs unipolar hemiarthroplasty
Mortality at 12 months · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
RR 1.17 [0.89, 1.53]8 studies · 839 participantsLow
Bipolar hemiarthroplasty vs unipolar hemiarthroplasty
Unplanned return to theatre (end of · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
RR 1.08 [0.44, 2.64]4 studies · 532 participantsVery low
Total hip arthroplasty vs hemiarthroplasty
Activities of daily living, early (within 4 months): using Katz Index and an undefined measurement tool to identify people who were independent · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
RR 1.03 [0.91, 1.18]2 studies · 225 participantsVery low
Total hip arthroplasty vs hemiarthroplasty
Delirium (end of · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
RR 1.41 [0.6, 3.33]2 studies · 357 participantsLow
Total hip arthroplasty vs hemiarthroplasty
Functional status, early (within 4 months): using HHS (range from 0 to 100) and Johansen hip score (range from 0 to 100); higher scores indicate better function · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
no estimate extracted3 studies · 395 participantsVery low
Cemented vs uncemented hemiarthroplasty
Delirium (end of · adults with displaced and undisplaced hip fractures; included studies were for intracapsular fractures, except for one…
Arthroplasties for hip fracture in adults (2022) · Cochrane
RR 1.06 [0.55, 2.06]2 studies · 800 participantsLow
Total hip arthroplasty vs hemiarthroplasty
HRQoL, early (within 4 months): using EQ‐5D (range from 0 to 1); higher scores indicate better quality of life · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
no estimate extracted2 studies · 279 participantsVery low
Total hip arthroplasty vs hemiarthroplasty
Mobility, early (within 4 months): using a 9‐point mobility scale; lower scores indicate better mobility · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
no estimate extracted1 study · 83 participantsLow
Total hip arthroplasty vs hemiarthroplasty
Mortality, early (within 4 months) · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
RR 0.77 [0.42, 1.42]6 studies · 725 participantsVery low
Total hip arthroplasty vs hemiarthroplasty
Mortality at 12 months · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
RR 1 [0.82, 1.34]11 studies · 2667 participantsModerate
Total hip arthroplasty vs hemiarthroplasty
Unplanned return to theatre (end of · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
RR 0.68 [0.41, 1.15]9 studies · 2476 participantsLow
Cemented vs uncemented hemiarthroplasty
Functional status, early (within 4 months): using HHS (range from 0 to 100); higher values indicate better function · adults with displaced and undisplaced hip fractures; included studies were for intracapsular fractures, except for one…
Arthroplasties for hip fracture in adults (2022) · Cochrane
no estimate extracted3 studies · 416 participantsVery low
Cemented vs uncemented hemiarthroplasty
HRQoL, early (within 4 months): using EQ‐5D (range 0 to 1), and SF‐12 (range 0 to 100); higher values indicate better quality of life. · adults with displaced and undisplaced hip fractures; included studies were for intracapsular fractures, except for one…
Arthroplasties for hip fracture in adults (2022) · Cochrane
no estimate extracted3 studies · 1122 participantsModerate
Cemented vs uncemented hemiarthroplasty
Mobility, early (within 4 months): able to walk outdoors using no more than 1 walking aid. · adults with displaced and undisplaced hip fractures; included studies were for intracapsular fractures, except for one…
Arthroplasties for hip fracture in adults (2022) · Cochrane
RR 1.04 [0.95, 1.14]3 studies · 980 participantsModerate
Cemented vs uncemented hemiarthroplasty
Mortality, early (within 4 months) · adults with displaced and undisplaced hip fractures; included studies were for intracapsular fractures, except for one…
Arthroplasties for hip fracture in adults (2022) · Cochrane
RR 95 [0.8, 1.13]12 studies · 3136 participantsLow
Cemented vs uncemented hemiarthroplasty
Mortality at 12 months · adults with displaced and undisplaced hip fractures; included studies were for intracapsular fractures, except for one…
Arthroplasties for hip fracture in adults (2022) · Cochrane
RR 0.86 [0.78, 0.96]15 studies · 3727 participantsModerate
Cemented vs uncemented hemiarthroplasty
Unplanned return to theatre (end of · adults with displaced and undisplaced hip fractures; included studies were for intracapsular fractures, except for one…
Arthroplasties for hip fracture in adults (2022) · Cochrane
RR 0.7 [0.45, 1.1]6 studies · 2336 participantsLow
Bipolar hemiarthroplasty vs unipolar hemiarthroplasty
Activities of daily living, early (within 4 months) · adults with displaced and undisplaced hip fractures
Arthroplasties for hip fracture in adults (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Limb function at 6 or 12 months · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures
Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open… (2022) · Cochrane
no estimate extractedNRNo studies
Timing of wound closure (immediate vs delayed)
Deep surgical site infection · adults with open long bone fractures of the upper and lower limbs
Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open… (2022) · Cochrane
RR 0.82 [0.37, 1.8]2 studies · 458 participantsVery low
Timing of wound closure (immediate vs delayed)
Delayed union or non‐union · adults with open long bone fractures of the upper and lower limbs
Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open… (2022) · Cochrane
RR 1.13 [0.83, 1.55]1 study · 387 participantsVery low
Timing of wound closure (immediate vs delayed)
Unplanned operations at 12 months · adults with open long bone fractures of the upper and lower limbs
Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open… (2022) · Cochrane
no estimate extractedNRNo studies
Timing of wound closure (immediate vs delayed)
Adverse events ‐ superficial infection · adults with open long bone fractures of the upper and lower limbs
Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open… (2022) · Cochrane
RR 6.45 [0.35, 120.43]1 study · 71 participantsVery low