What do systematic reviews say?

1,655 questions · 1,751 findings · 147 reviews · Pain, Palliative and Supportive Care

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No studies found 361 · 20.6%GRADE not reported 87 · 5%Very low 625 · 35.7%Low 367 · 21%Moderate 232 · 13.2%High 79 · 4.5%

Medically assisted hydration vs usual care

Quality of life · adults aged 18 years and older receiving palliative care

The review found no eligible studies for this question.

1 finding from 1 review

Medically assisted hydration for adults receiving palliative care 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Medically assisted hydration vs usual care

Survival Cox regression model Study enrolment to last date of · adults aged 18 years and older receiving palliative care

1 finding from 1 review

Medically assisted hydration for adults receiving palliative care 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 200 participants
Very low

Medically assisted hydration vs usual care

Adverse events Participant events · adults aged 18 years and older receiving palliative care

1 finding from 1 review

Medically assisted hydration for adults receiving palliative care 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 242 participants
Very low

Non‐nutritive sucking (NNS) vs no intervention

Pain reactivity (first 30 seconds post‐procedure) · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 597 participants
Very low

Facilitated tucking vs no intervention

Pain reactivity (first 30 seconds post‐procedure) · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 733 participants
Very low

Facilitated tucking vs no intervention

Immediate pain regulation (between 30 seconds and 5 minutes post‐procedure) · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 557 participants
Very low

Facilitated tucking vs no intervention

Adverse events · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 299 participants
Very low

Structured parent involvement vs no intervention

Pain reactivity (first 30 seconds post‐procedure) · full‐term born older infants

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 653 participants
Moderate

Structured parent involvement vs no intervention

Immediate pain regulation (between 30 seconds and 5 minutes post‐procedure) · full‐term born older infants

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 728 participants
Low

Structured parent involvement vs no intervention

Adverse events · full‐term born older infants

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 854 participants
Low

Non‐nutritive sucking (NNS) vs no intervention

Immediate pain regulation (between 30 seconds and 5 minutes post‐procedure) · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 379 participants
Very low

Non‐nutritive sucking (NNS) vs no intervention

Adverse events · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 318 participants
Very low

Non‐nutritive sucking (NNS) vs no intervention

Pain reactivity (first 30 seconds post‐procedure) · full‐term born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 545 participants
Very low

Non‐nutritive sucking (NNS) vs no intervention

Immediate pain regulation (between 30 seconds and 5 minutes post‐procedure) · full‐term born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 536 participants
Very low

Non‐nutritive sucking (NNS) vs no intervention

Adverse events · full‐term born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 507 participants
Very low

Swaddling vs no intervention

Pain reactivity (first 30 seconds post‐procedure) · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 468 participants
Very low

Swaddling vs no intervention

Immediate pain regulation (between 30 seconds and 5 minutes post‐procedure) · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 204 participants
Very low

Swaddling vs no intervention

Adverse events · preterm born neonates

1 finding from 1 review

Non‐pharmacological management of infant and young child procedural pain 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 304 participants
Low

Application of heat vs application of cold

At least a clinically significant reduction in pain within 6 hours Reported in studies as: clinically improved or reduced pain,a or cessation of pain at end of treatmentb · people stung accidentally by bluebottle jellyfish (Physalia) and box jellyfish that do not cause Irukandji syndrome (Hawaiian box…

It is very uncertain whether application of heat changes at least a clinically significant reduction in pain within 6 hours… compared with application of cold (very low certainty).

1 finding from 1 review

Interventions for the symptoms and signs resulting from jellyfish stings 2023 · Cochrane Headline outcomes only
RR 2.25 [1.42, 3.56]
2 studies · 142 participants
Very low

Intervention not reported

Clinically significant reduction in pain · people stung accidentally by box jellyfish that do not cause Irukandji syndrome (Hawaiian box jellyfish; Carybdea alata) and healthy…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the symptoms and signs resulting from jellyfish stings 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found