Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

141 questions · 155 findings · 23 reviews · Headline outcomes only

No studies found 50 · 32.3%GRADE not reported 1 · 0.6%Very low 27 · 17.4%Low 39 · 25.2%Moderate 28 · 18.1%High 10 · 6.5%

Trifocal intraocular lenses vs bifocal intraocular lenses after cataract extraction among participants with presbyopia

Mean quality of life or visual function (measured using Visual Function Index‐14 tool) (1 year) · participants (> 30 years) with cataract and presbyopia

The review found no eligible studies for this question.

1 finding from 1 review

Multifocal vs monofocal intraocular lenses after cataract extraction

Distance visual acuity ‐ less than 6/6 unaided · people with cataract

Multifocal showed no clear difference in unaided distance visual acuity worse than 6/6 compared with monofocal intraocular lenses after cataract extraction (moderate certainty).

1 finding from 1 review

Vaginal PGE2 pessary vs vaginal PGE2

Caesarean section · women with a previous caesarean section, a live singleton fetus (37‐42 weeks of gestation) in cephalic presentation and a reactive…

It is very uncertain whether vaginal PGE2 pessary changes caesarean section compared with vaginal PGE2 tablet (very low certainty).

1 finding from 1 review

Phacoemulsification vs laser peripheral iridotomy

Proportion of participants with IOP control (higher number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

Phacoemulsification may leads to higher proportion of participants with IOP control (higher number of events… compared with laser peripheral iridotomy (low certainty).

1 finding from 1 review

Phacoemulsification vs laser peripheral iridotomy

Proportion of participants requiring further IOP‐lowering interventions (additional surgery, medications, or both) (lower number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

It is very uncertain whether phacoemulsification changes proportion of participants requiring further IOP‐lowering… compared with laser peripheral iridotomy (very low certainty).

1 finding from 1 review

Phacoemulsification vs laser peripheral iridotomy

Proportion of participants with 1 or more recurrent APAC episodes in the same eye (lower number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

It is very uncertain whether phacoemulsification changes proportion of participants with 1 or more recurrent APAC episodes in… compared with laser peripheral iridotomy (very low certainty).

1 finding from 1 review