Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

105 questions · 107 findings · 15 reviews

No studies found 3 · 2.8%GRADE not reported 13 · 12.1%Very low 36 · 33.6%Low 30 · 28%Moderate 23 · 21.5%High 2 · 1.9%

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Infant Mortality at 12 months · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

Kesho Bora: AZT/3TC/LPV‐r showed no clear difference in infant Mortality at 12 months compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (low certainty).

1 finding from 1 review

Bae: AZT/3TC/NVP vs Other Short Course Regimen

Maternal Grade 3/4 Severe Adverse Events Requiring Treatment Modification · HIV‐infected pregnant women

It is very uncertain whether tonwe‐Gold: AZT/3TC/NVP changes maternal Grade 3/4 Severe Adverse Events Requiring Treatment… compared with other Short Course Regimen (very low certainty).

1 finding from 1 review

Bae: AZT/3TC/NVP vs Other Short Course Regimen

Mother to Child Transmission at 1 Month · HIV‐infected pregnant women

It is very uncertain whether tonwe‐Gold continued: AZT/3TC/NVP changes mother to Child Transmission of HIV at 1 Month compared with other Short Course Regimen (very low certainty).

1 finding from 1 review

Bae: AZT/3TC/NVP vs Other Short Course Regimen

Mother to Child Transmission at 12 Months · HIV‐infected pregnant women

It is very uncertain whether tonwe‐Gold continued: AZT/3TC/NVP changes mother to Child Transmission of HIV at 12 Months compared with other Short Course Regimen (very low certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Maternal Grade 3/4 Severe Adverse Events · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

It is very uncertain whether kesho Bora: AZT/3TC/LPV‐r changes maternal Grade 3/4 Severe Adverse Events compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (very low certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Infant Grade 3/4 Severe Adverse Events · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

Kesho Bora: AZT/3TC/LPV‐r showed no clear difference in infant Grade 3/4 Severe Adverse Events compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (low certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Prematurity · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

It is very uncertain whether kesho Bora: AZT/3TC/LPV‐r changes prematurity compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (very low certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Low birthweight · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

Kesho Bora continued: AZT/3TC/LPV‐r showed no clear difference in low Birth Weight compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (low certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Stillbirth · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

Kesho Bora continued: AZT/3TC/LPV‐r showed no clear difference in stillbirths compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (low certainty).

1 finding from 1 review

Intervention not reported

Treatment failure at 1 month or less · patients with acute otitis media

The intervention led to higher treatment failure at 1 month or less; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 8 to 19 days · patients with acute otitis media

The intervention led to higher treatment failure at 8 to 19 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 20 to 30 days · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 20 to 30 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 8 to 19 days · patients with acute otitis media

The intervention led to higher treatment failure at 8 to 19 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 20 to 30 days · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 20 to 30 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 3 months or less · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 3 months or less; GRADE not reported.

1 finding from 1 review