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Evidence found and GRADE certainty

350 questions · 352 findings · 52 reviews

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No studies found 87 · 24.7%GRADE not reported 32 · 9.1%Very low 98 · 27.8%Low 67 · 19%Moderate 58 · 16.5%High 10 · 2.8%

Conscious sedation and analgesia (CSA) + paracervical block (PCB) vs CSA

Side effects (postoperative vomiting and/or vomiting) · women undergoing oocyte retrieval for assisted reproduction

It is very uncertain whether conscious sedation and analgesia (CSA) + paracervical block (PCB) changes side effects (postoperative vomiting and/or vomiting) compared with CSA (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Adverse effects (central nervous system) · people with depression after stroke

It is very uncertain whether pharmacological interventions changes adverse events: all ‐ central nervous system events (e.g. confusion,… compared with placebo (very low certainty).

1 finding from 1 review

Phenobarbital vs levetiracetam

Proportion of infants who develop sedation or drowsiness · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop sedation or drowsiness compared with levetiracetam (very low certainty).

1 finding from 1 review

Phenobarbital vs phenytoin

Proportion of infants who develop sedation or drowsiness · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop sedation or drowsiness compared with phenytoin (very low certainty).

1 finding from 1 review

Phenobarbital vs lorazepam

Proportion of infants who develop sedation or drowsiness · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop sedation or drowsiness compared with lorazepam (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Phenytoin vs lorazepam

Proportion of infants who develop sedation or drowsiness · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Phenytoin changes proportion of infants who develop sedation or drowsiness compared with lorazepam (very low certainty).

1 finding from 1 review

Phenobarbital vs levetiracetam

Proportion of infants who develop sedation or drowsiness · neonates with EEG‐confirmed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop sedation or drowsiness compared with levetiracetam (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Remifentanil vs diazepam

Maternal OAA score (observer assessment of alertness/sedation) < 4 (Maternal sedation measured using sedation scores as defined by authors) · health problem or population

Summary of findings table ‐ Remifentanil may leads to lower maternal OAA score (observer assessment of alertness/sedation) < 4… compared with diazepam (low certainty).

1 finding from 1 review

Antihistamines vs scopolamine

Adverse effects: 1. Sedation · patients with motion sickness

It is very uncertain whether antihistamines changes adverse effects: sedation Assessed by: self‐reported compared with scopolamine (very low certainty).

1 finding from 1 review

Antihistamines vs acupuncture

Adverse effects: sedation, impaired cognitive function, blurred vision · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review