Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention
Progression of retinopathy · type 1 or type 2 diabetics
1 finding from 1 review
- no estimate extracted1 participantsGRADE not reported
Findings
What do systematic reviews say?
322 questions · 324 findings · 25 reviews · Eyes and Vision
No studies found 77 · 23.8%GRADE not reported 5 · 1.5%Very low 77 · 23.8%Low 64 · 19.8%Moderate 91 · 28.1%High 10 · 3.1%
Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention
Combined incidence and progression of diabetic retinopathy by 5 years · type 1 or type 2 diabetics
1 finding from 1 review
- no estimate extracted1 participantsGRADE not reported
Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention
Incidence of PDR/CSME/VH by 5 years · type 1 or type 2 diabetics
1 finding from 1 review
- no estimate extracted1 participantsGRADE not reported
Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention
Change in visual loss associated with PSR: visual loss is defined by the deterioration of visual acuity of 3 lines or more with the Snellen chart · type 1 or type 2 diabetics
It is very uncertain whether blood pressure intervention/intensive blood pressure intervention changes visual acuity (loss of 3 lines or more) by 5 years compared with placebo/standard blood pressure intervention (very low certainty).
1 finding from 1 review
- RR 1.15 [0.63, 2.08]2 studies · 2326 participantsVery low
Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention
Adverse events—all‐cause mortality · type 1 or type 2 diabetics
1 finding from 1 review
- no estimate extracted1 participantsGRADE not reported
Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention
Adverse events: hypotension · type 1 or type 2 diabetics
Blood pressure intervention/intensive blood pressure intervention may leads to higher adverse events—hypotension compared with placebo/standard blood pressure intervention (low certainty).
1 finding from 1 review
- RR 2.04 [1.63, 2.55]2 studies · 3323 participantsLow
Intervention not reported
High‐dose atropine (≥ 0.5%) · children with progressive myopia (38 studies, 6525 participants in analyses) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
- Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 512 participantsModerate
Intervention not reported
Undercorrected single vision spectacles · children with progressive myopia (38 studies, 6525 participants in analyses) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
- Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 72 participantsLow
Intervention not reported
High‐dose atropine (≥ 0.5%) · children with progressive myopia (26 studies, 4949 participants in the analysis) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
- Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 428 participantsModerate
Intervention not reported
Moderate‐dose atropine (0.1% to < 0.5%) · children with progressive myopia (26 studies, 4949 participants in the analysis) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
- Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 247 participantsLow
Intervention not reported
Low‐dose atropine (< 0.1%) · children with progressive myopia (26 studies, 4949 participants in the analysis) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
- Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 249 participantsLow
Intervention not reported
Pirenzepine · children with progressive myopia (26 studies, 4949 participants in the analysis) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
- Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes onlyno estimate extracted1 study · 53 participantsLow
Intervention not reported
Multifocal soft contact lenses · children with progressive myopia (26 studies, 4949 participants in the analysis) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
- Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes onlyno estimate extracted5 studies · 540 participantsLow
Intervention not reported
Rigid gas‐permeable contact lenses · children with progressive myopia (26 studies, 4949 participants in the analysis) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
- Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 154 participantsVery low
Intervention not reported
Peripheral plus spectacle lenses · children with progressive myopia (26 studies, 4949 participants in the analysis) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
- Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 188 participantsVery low
Intervention not reported
Multifocal spectacle lenses · children with progressive myopia (26 studies, 4949 participants in the analysis) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
- Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes onlyno estimate extracted8 studies · 696 participantsLow
Intervention not reported
Undercorrected single vision spectacles · children with progressive myopia (26 studies, 4949 participants in the analysis) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
- Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 122 participantsVery low
Intervention not reported
Moderate‐dose atropine (0.1% to < 0.5%) · children with progressive myopia (38 studies, 6525 participants in analyses) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
- Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 254 participantsModerate
Intervention not reported
High‐dose atropine (≥ 0.5%) · children with progressive myopia (36 studies, 6263 participants) in the analysis Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
- Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 512 participantsModerate
Intervention not reported
Moderate‐dose atropine (0.1% to < 0.5%) · children with progressive myopia (36 studies, 6263 participants) in the analysis Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
- Interventions for myopia control in children: a living systematic review and network meta‐analysis 2023 · Cochrane Headline outcomes onlyno estimate extracted1 study · 155 participantsModerate