Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

272 questions · 281 findings · 42 reviews · Headline outcomes only

No studies found 62 · 22.1%GRADE not reported 5 · 1.8%Very low 68 · 24.2%Low 100 · 35.6%Moderate 37 · 13.2%High 9 · 3.2%

Intervention not reported

Self‐Care Practice (Denyes Self‐Care Practice Instrument (DSCPI) · adolescents between 12 and 19 years with any chronic condition requiring ongoing clinical care, who are leaving or transitioning from…
1 finding from 1 review

Intervention not reported

Disease‐specific outcomes · adolescents between 12 and 19 years with any chronic condition requiring ongoing clinical care, who are leaving or transitioning from…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Disease specific status (Activity index, clinical inventory) · adolescents between 12 and 19 years with any chronic condition requiring ongoing clinical care, who are leaving or transitioning from…
1 finding from 1 review

Intervention not reported

Well‐being measures · adolescents between 12 and 19 years with any chronic condition requiring ongoing clinical care, who are leaving or transitioning from…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Successful cannulation at the first attempt · paediatric patients

The intervention probably leads to higher successful cannulation at the first attempt (moderate certainty).

1 finding from 1 review

Intervention not reported

Rate of complications (haematoma or ischaemia) · paediatric patients

The intervention probably leads to lower rate of complications (haematoma or ischaemia) (moderate certainty).

1 finding from 1 review

Intervention not reported

Successful cannulation within the first 2 attempts · paediatric patients

The intervention probably leads to higher successful cannulation within the first 2 attempts (moderate certainty).

1 finding from 1 review

Etanercept vs placebo

Percentage of participants reaching PASI 75 · people with paediatric psoriasis

Etanercept leads to higher PASI 75 Participants achieving a 75% improvement in the Psoriasis… compared with placebo (high certainty).

1 finding from 1 review

Etanercept vs placebo

PASI 50 · people with paediatric psoriasis

Etanercept leads to higher PASI 50 Participants achieving a 50% improvement in the Psoriasis… compared with placebo (high certainty).

1 finding from 1 review

Etanercept vs placebo

PASI 90 · people with paediatric psoriasis

Etanercept leads to higher PASI 90 Participants achieving a 90% improvement in the Psoriasis… compared with placebo (high certainty).

1 finding from 1 review

Etanercept vs placebo

PGA Participants achieving a PGA of 'clear' or 'almost clear' · people with paediatric psoriasis

Etanercept leads to higher PGA Participants achieving a PGA of 'clear' or 'almost clear' compared with placebo (high certainty).

1 finding from 1 review

Etanercept vs placebo

CDLQI Scores range from 0 to 30. Lower scores indicate better health‐related quality of life. Calculations are based on the change from baseline to week 12 in both groups · people with paediatric psoriasis
1 finding from 1 review

Induction and maintenance: sevoflurane + nitrous oxide (N2O) vs propofol + N2O

Number of patients with postoperative nausea and vomiting (postoperative care unit) · paediatric

Induction and maintenance: sevoflurane + nitrous oxide (N2O) may leads to higher postoperative nausea and vomiting compared with propofol + N2O (low certainty).

1 finding from 1 review

Induction and maintenance: sevoflurane + nitrous oxide (N2O) vs propofol + N2O

Postoperative behavioural disturbances Different scales · paediatric

It is very uncertain whether induction and maintenance: sevoflurane + nitrous oxide (N2O) changes postoperative behavioural disturbances Different scales compared with propofol + N2O (very low certainty).

1 finding from 1 review

Induction and maintenance: sevoflurane + nitrous oxide (N2O) vs propofol + N2O

Intraoperative and postoperative respiratory and cardiovascular complications · paediatric

It is very uncertain whether induction and maintenance: sevoflurane + nitrous oxide (N2O) changes intraoperative and postoperative respiratory and cardiovascular… compared with propofol + N2O (very low certainty).

1 finding from 1 review

Maintenance anaesthesia: inhalational vs intravenous

Nausea and vomiting ‐ subgroup analysis: thiopentone or halothane + N2O versus propofol or propofol + N2O · paediatric

Maintenance anaesthesia: inhalational may leads to higher nausea and vomiting ‐ subgroup analysis: thiopentone or halothane +… compared with intravenous (low certainty).

2 findings from 1 review