Question · asked by 1 review

Etanercept vs placebo: Percentage of participants reaching PASI 75

Etanercept leads to higher PASI 75 Participants achieving a 75% improvement in the Psoriasis… compared with placebo (high certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Etanercept vs placebo
PASI 75 Participants achieving a 75% improvement in the Psoriasis Area and Severity Index · people with paediatric psoriasis
Etanercept leads to higher PASI 75 Participants achieving a 75% improvement in the Psoriasis… compared with placebo (high certainty).
Anti‐TNF agents for paediatric psoriasis (2015) · Cochrane Headline outcomes only
RR 4.95 [2.83, 8.65]1 study · 211 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Anti‐TNF agents for paediatric psoriasis
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.