Varenicline vs e‐cigarettes
It is very uncertain whether varenicline changes smoking abstinence at longest compared with e‐cigarettes (very low certainty).
- RR 3.25 [1.21, 8.71]1 study · 54 participantsVery low
It is very uncertain whether varenicline changes smoking abstinence at longest compared with e‐cigarettes (very low certainty).
Varenicline showed no clear difference in neuropsychiatric SAEs (varenicline vs placebo or no medication) compared with placebo or no medication (low certainty).
Varenicline showed no clear difference in cardiac SAEs (varenicline vs placebo or no medication) compared with placebo or no medication (low certainty).
Cytisine probably leads to higher smoking abstinence at longest compared with placebo or no medication (moderate certainty).
Cytisine showed no clear difference in SAEs (cytisine vs placebo or no medication) compared with placebo or no medication (low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
Cytisine showed no clear difference in smoking abstinence at longest compared with varenicline (low certainty).
It is very uncertain whether the intervention changes smoking cessation ‐ oral spray versus gum (very low certainty).
It is very uncertain whether the intervention changes smoking cessation ‐ oral spray versus inhaler (very low certainty).
It is very uncertain whether the intervention changes smoking cessation ‐ gum versus inhaler (very low certainty).
The intervention leads to higher smoking cessation at 6+ months (high certainty).