What do systematic reviews say?

CBT vs TRT (directive counselling and bilateral masking)

• Cognitive behavioural therapy for tinnitus 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 42 participants
  Low

CBT vs TRT (directive counselling and bilateral masking)

• Cognitive behavioural therapy for tinnitus 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 42 participants
  Low

LMA vs BMV

LMA probably leads to lower failure with primary modality of resuscitation compared with BMV (moderate certainty).

• Laryngeal mask airway versus bag‐mask ventilation or endotracheal intubation for neonatal resuscitation 2018 · Cochrane Headline outcomes only
  RR 0.16 [0.09, 0.3]
  5 studies · 660 participants
  Moderate

LMA vs endotracheal intubation

LMA showed no clear difference in death or HIE compared with endotracheal intubation (low certainty).

• Laryngeal mask airway versus bag‐mask ventilation or endotracheal intubation for neonatal resuscitation 2018 · Cochrane Headline outcomes only
  RR 0.59 [0.11, 3.32]
  1 study · 68 participants
  Low

LMA vs BMV

LMA probably leads to lower need for intubation compared with BMV (moderate certainty).

• Laryngeal mask airway versus bag‐mask ventilation or endotracheal intubation for neonatal resuscitation 2018 · Cochrane Headline outcomes only
  RR 0.24 [0.12, 0.47]
  5 studies · 660 participants
  Moderate

LMA vs BMV

LMA probably leads to lower apgar score ≤ 7 at 5 minutes compared with BMV (moderate certainty).

• Laryngeal mask airway versus bag‐mask ventilation or endotracheal intubation for neonatal resuscitation 2018 · Cochrane Headline outcomes only
  RR 0.34 [0.16, 0.74]
  2 studies · 511 participants
  Moderate

LMA vs BMV

LMA probably leads to lower admission to NICU compared with BMV (moderate certainty).

• Laryngeal mask airway versus bag‐mask ventilation or endotracheal intubation for neonatal resuscitation 2018 · Cochrane Headline outcomes only
  RR 0.6 [0.4, 0.9]
  2 studies · 191 participants
  Moderate

LMA vs BMV

LMA showed no clear difference in death or HIE compared with BMV (low certainty).

• Laryngeal mask airway versus bag‐mask ventilation or endotracheal intubation for neonatal resuscitation 2018 · Cochrane Headline outcomes only
  RR 0.65 [0.17, 2.43]
  2 studies · 191 participants
  Low

LMA vs endotracheal intubation

It is very uncertain whether LMA changes failure to correctly insert the device compared with endotracheal intubation (very low certainty).

• Laryngeal mask airway versus bag‐mask ventilation or endotracheal intubation for neonatal resuscitation 2018 · Cochrane Headline outcomes only
  RR 0.95 [0.17, 5.42]
  3 studies · 158 participants
  Very low

LMA vs endotracheal intubation

It is very uncertain whether LMA changes successful insertion of device at first attempt compared with endotracheal intubation (very low certainty).

• Laryngeal mask airway versus bag‐mask ventilation or endotracheal intubation for neonatal resuscitation 2018 · Cochrane Headline outcomes only
  RR 1.01 [0.89, 1.14]
  2 studies · 108 participants
  Very low

LMA vs endotracheal intubation

LMA showed no clear difference in apgar score ≤ 7 at 5 minutes compared with endotracheal intubation (low certainty).

• Laryngeal mask airway versus bag‐mask ventilation or endotracheal intubation for neonatal resuscitation 2018 · Cochrane Headline outcomes only
  RR 0.7 [0.34, 1.45]
  2 studies · 108 participants
  Low

LMA vs endotracheal intubation

LMA showed no clear difference in soft tissue trauma after device inserted compared with endotracheal intubation (low certainty).

• Laryngeal mask airway versus bag‐mask ventilation or endotracheal intubation for neonatal resuscitation 2018 · Cochrane Headline outcomes only
  RR 2 [0.58, 6.91]
  1 study · 40 participants
  Low

Early removal of the LMA vs late removal of the LMA after general anaesthesia

Early removal of the LMA showed no clear difference in laryngospasm (immediate) compared with late removal of the LMA after general anaesthesia (low certainty).

• Early versus late removal of the laryngeal mask airway (LMA) for general anaesthesia 2015 · Cochrane Headline outcomes only
  RR 1.23 [0.74, 2.03]
  11 studies · 1615 participants
  Low

Early removal of the LMA vs late removal of the LMA after general anaesthesia

It is very uncertain whether early removal of the LMA changes desaturation (immediate) compared with late removal of the LMA after general anaesthesia (very low certainty).

• Early versus late removal of the laryngeal mask airway (LMA) for general anaesthesia 2015 · Cochrane Headline outcomes only
  RR 0.68 [0.4, 1.16]
  13 studies · 2037 participants
  Very low

Early removal of the LMA vs late removal of the LMA after general anaesthesia

Early removal of the LMA may leads to higher airway obstruction (immediate) compared with late removal of the LMA after general anaesthesia (low certainty).

• Early versus late removal of the laryngeal mask airway (LMA) for general anaesthesia 2015 · Cochrane Headline outcomes only
  RR 2.69 [1.32, 5.5]
  8 studies · 1313 participants
  Low

Early removal of the LMA vs late removal of the LMA after general anaesthesia

It is very uncertain whether early removal of the LMA changes coughing (immediate) compared with late removal of the LMA after general anaesthesia (very low certainty).

• Early versus late removal of the laryngeal mask airway (LMA) for general anaesthesia 2015 · Cochrane Headline outcomes only
  RR 0.52 [0.29, 0.94]
  11 studies · 1430 participants
  Very low