Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

136 questions · 140 findings · 17 reviews · Vascular

No studies found 22 · 15.7%GRADE not reported 13 · 9.3%Very low 28 · 20%Low 50 · 35.7%Moderate 18 · 12.9%High 9 · 6.4%

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Target lesion revascularization · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon may leads to lower target lesion revascularization compared with uncoated balloon angioplasty at 12 months (low certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Binary restenosis · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon probably leads to lower binary restenosis compared with uncoated balloon angioplasty at 12 months (moderate certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Death · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon showed no clear difference in death compared with uncoated balloon angioplasty at 12 months (high certainty).

1 finding from 1 review

Intervention not reported

30‐Day amputation‐free survival · patients with less than 42 days' lower limb ischaemia
1 finding from 1 review

Intervention not reported

30‐Day mortality · patients with less than 42 days' lower limb ischaemia
1 finding from 1 review

Intervention not reported

Vessel patency ( · patients with less than 42 days' lower limb ischaemia

It is very uncertain whether the intervention changes vessel patency ( (very low certainty).

1 finding from 1 review

Intervention not reported

Major bleeding ( · patients with less than 42 days' lower limb ischaemia

It is very uncertain whether the intervention changes major bleeding ( (very low certainty).

1 finding from 1 review