Cochrane · systematic review · CD015232

Tourniquet use for people with peripheral arterial disease undergoing major lower limb amputations

Laloo, R, Dewi, M, Gwilym, BL, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

VascularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 4 · 57.1%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Tourniquet use compared with no tourniquet use for major lower limb amputations in people with peripheral arterial disease

Population: people with PAD undergoing MLLA
7 questions
OutcomeEffectEvidenceStatus / GRADE
Intraoperative blood loss (mL) (
Tourniquet use vs no tourniquet use
no estimate extracted1 study · 54 participantsLow
Downgraded: risk of bias, imprecision
Fall in haemoglobin levels(g/L or mmol/L) (
Tourniquet use vs no tourniquet use
no estimate extracted1 study · 54 participantsLow
Downgraded: risk of bias, imprecision
Perioperative blood transfusion requirement (
Tourniquet use vs no tourniquet use
no estimate extracted1 study · 54 participantsLow
Downgraded: risk of bias, imprecision
Primary wound‐healing rates (6 weeks)
Tourniquet use vs no tourniquet use
no estimate extracted1 study · 54 participantsVery low
Downgraded: risk of bias, imprecision
Stump revision rates (maximal
Tourniquet use vs no tourniquet use
no estimate extracted1 study · 54 participantsVery low
Downgraded: risk of bias, imprecision
Postoperative complications (maximal
Tourniquet use vs no tourniquet use
no estimate extracted1 study · 54 participantsVery low
Downgraded: risk of bias, imprecision
Postoperative mortality (6 weeks)
Tourniquet use vs no tourniquet use
no estimate extracted1 study · 54 participantsVery low
Downgraded: risk of bias, imprecision