Any other adverse effects of the interventions, such as gingival disease and demineralisation · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
The review found no eligible studies for this question.
1 finding from 1 review
Number of participants referred for surgical exposure of the PDC · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
It is very uncertain whether double primary (canine and first molar) tooth extraction changes number of participants referred for surgical exposure of the PDC compared with single primary (canine) tooth extraction (very low certainty).
1 finding from 1 review
Costs and cost‐effectiveness · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
The review found no eligible studies for this question.
1 finding from 1 review
Reported improvement in the position of the ectopic canine measured from radiographs · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Patient‐reported outcome measures (PROMs) · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Time taken for the canine to erupt into the mouth · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Overall treatment time wearing orthodontic appliances · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Fixation and stabilisation (splint type/duration) vs Different splint, no splint, or different splinting duration
Outcome not reported · People with avulsed and replanted permanent (front) teeth
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Tooth survival · People with avulsed and replanted permanent (front) teeth
It is very uncertain whether hyperbaric oxygen (following replantation) changes tooth survival at 12 months compared with control (very low certainty).
1 finding from 1 review
Adverse effects · People with avulsed and replanted permanent (front) teeth
1 finding from 1 review
Day 2012 used a formal methodology to identify and report adverse effects, with none identified.
1 study · 22 participants
GRADE not reported
Tooth survival · People with avulsed and replanted permanent (front) teeth
It is very uncertain whether thymosin alpha 1 (10-minute soak prior to replantation) changes tooth survival at 12 months compared with control (saline) (very low certainty).
2 findings from 1 review
Adverse effects · People with avulsed and replanted permanent (front) teeth
1 finding from 1 review
Aesthetics (discolouration) at 12 months (patient level) · People with avulsed and replanted permanent (front) teeth
It is very uncertain whether ledermix root canal medicament (day 0 to 10) changes aesthetics (discolouration) at 12 months (patient level) compared with ultracal root canal medicament (day 7 to 10) (very low certainty).
1 finding from 1 review
Treatment with antibiotics vs No antibiotics, placebo, or different types of antibiotics
Outcome not reported · People with avulsed and replanted permanent (front) teeth
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Pain · People with avulsed and replanted permanent (front) teeth
1 finding from 1 review
Adverse effects · People with avulsed and replanted permanent (front) teeth
1 finding from 1 review
Adverse effects · People with avulsed and replanted permanent (front) teeth
1 finding from 1 review
Tooth survival · People with avulsed and replanted permanent (front) teeth
1 finding from 1 review
Tooth survival at 12 months: Not estimable (due to no events in either arm); 27 teeth in 22 patients (1 RCT). At 12 months, no teeth were lost. 1 tooth was lost at 16 months in the Ultracal group.
1 study · 22 participants
Very low
Storage of the tooth prior to replantation (storage medium) vs Different storage medium or dry storage
Outcome not reported · People with avulsed and replanted permanent (front) teeth
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Radiographic resorption (proxy measure for periodontal healing) at 12 months · People with avulsed and replanted permanent (front) teeth
It is very uncertain whether extra-oral pulp extirpation at day 0 changes radiographic resorption (proxy measure for periodontal healing) at… compared with intra-oral pulp extirpation at day 7 (very low certainty).
1 finding from 1 review