Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

219 questions · 223 findings · 25 reviews · Eyes and Vision

No studies found 76 · 34.1%GRADE not reported 5 · 2.2%Very low 39 · 17.5%Low 75 · 33.6%Moderate 25 · 11.2%High 3 · 1.3%

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without pan‐retinal photocoagulation (PRP) vs PRP alone

Complete regression of new vessels (dichotomous outcome) · proliferative diabetic retinopathy

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without… probably leads to higher complete regression of new vessels (dichotomous outcome) compared with PRP alone (moderate certainty).

1 finding from 1 review

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without pan‐retinal photocoagulation (PRP) vs PRP alone

Presence of vitreous haemorrhaged · proliferative diabetic retinopathy

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without… probably leads to lower presence of vitreous haemorrhaged compared with PRP alone (moderate certainty).

1 finding from 1 review

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without pan‐retinal photocoagulation (PRP) vs PRP alone

Need for vitrectomy · proliferative diabetic retinopathy

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without… may leads to lower need for vitrectomy compared with PRP alone (low certainty).

1 finding from 1 review