Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

119 questions · 120 findings · 9 reviews

No studies found 51 · 42.5%GRADE not reported 5 · 4.2%Very low 29 · 24.2%Low 29 · 24.2%Moderate 6 · 5%High 0 · 0%

Dornase alfa vs hypertonic saline

FEV1 · children with cystic fibrosis

Dornase alfa may leads to higher mean relative percentage in FEV1 (L) at 3 months compared with hypertonic saline (low certainty).

1 finding from 1 review

Dornase alfa vs hypertonic saline

Mean relative percentage in FVC (L) at 3 months · children with cystic fibrosis

Dornase alfa showed no clear difference in mean relative percentage in FVC (L) at 3 months compared with hypertonic saline (low certainty).

1 finding from 1 review

Dornase alfa vs hypertonic saline

Mean relative percentage in quality of life score at 3 months · children with cystic fibrosis

Dornase alfa showed no clear difference in mean relative percentage in quality of life score at 3 months compared with hypertonic saline (low certainty).

1 finding from 1 review

Magnesium sulphate vs hypertonic saline

Clinical severity score (CSS) (RDAI score; range 0 to 17; higher = poorer outcomes) measured 25 to 48 hoursafter treatment · children up to 12 months old with acute bronchiolitis

It is very uncertain whether magnesium sulphate changes clinical severity score (CSS) (RDAI score; range 0 to 17; higher =… compared with hypertonic saline (very low certainty).

1 finding from 1 review