Question · asked by 1 review

Mannitol vs hypertonic saline: Inadequate brain relaxation 3‐ or 4‐point scalesa

Population
patients with brain relaxation undergoing craniotomy
Intervention
Mannitol
Comparison
hypertonic saline
Outcome
Inadequate brain relaxation 3‐ or 4‐point scalesa

Mannitol may leads to lower inadequate brain relaxation 3‐ or 4‐point scalesa compared with hypertonic saline (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Mannitol vs hypertonic saline
Inadequate brain relaxation 3‐ or 4‐point scalesa · patients with brain relaxation undergoing craniotomy
Mannitol may leads to lower inadequate brain relaxation 3‐ or 4‐point scalesa compared with hypertonic saline (low certainty).
Mannitol versus hypertonic saline for brain relaxation in patients undergoing craniotomy (2014) · Cochrane Headline outcomes only
RR 0.6 [0.44, 0.83]3 studies · 387 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Mannitol versus hypertonic saline for brain relaxation in patients undergoing craniotomy
2014 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.