Development of >=1 new carious lesion (caries incidence) · Caries-free children to young adults with premolars/molars requiring pit-and-fissure sealants
In the single study reporting it, caries incidence was 0% in both the laser-alone and acid-etching groups (ungraded, single study).
1 finding from 1 review
Karaman 2013 (Er,Cr:YSGG laser vs acid-etching): incidence of caries was 0% in both groups; not meta-analyzed.
1 study · 16 participants
GRADE not reported
Acceptability · Caries-free children to young adults with premolars/molars requiring pit-and-fissure sealants
Both laser and acid-etching preparation were well accepted by patients (VAS, P = 1.000; ungraded, single study).
1 finding from 1 review
Kumar 2016 (Er,Cr:YSGG laser vs acid-etching): patient acceptance scored on a visual analogue scale; both preparations well accepted, P = 1.000; no significant difference.
1 study · 50 participants
GRADE not reported
Clinical (chair-side) time · Caries-free children to young adults with premolars/molars requiring pit-and-fissure sealants
Laser conditioning was reported to take less chair-side time than acid-etching in the studies that measured it, but times were not pooled (ungraded, narrative).
1 finding from 1 review
Walsh 1996 reported laser conditioning time of 7 s vs 70 s for acid preparation; Kumar 2016 reported Er,Cr:YSGG exposure ~10 s vs >35 s for acid etching; laser conditioning was shorter but times were not pooled, and…
2 studies
GRADE not reported
Sealant retention rate (completely retained) · Caries-free children to young adults with premolars/molars requiring pit-and-fissure sealants
At 18 months, laser preparation alone did not differ significantly from acid-etching for sealant retention (OR 0.82, 95% CI 0.23 to 2.85; ungraded, single study, high risk of bias).
6 findings from 1 review
OR 0.82 [0.23, 2.85]
1 study · 16 participants
GRADE not reported
OR 1.22 [0.69, 2.16]
3 studies · 80 participants
GRADE not reported
OR 1.05 [0.61, 1.80]
3 studies · 73 participants
GRADE not reported
Show 3 more findings
OR 2.78 [0.87, 8.91]
2 studies · 65 participants
GRADE not reported
OR 1.15 [0.63, 2.10]
1 study · 43 participants
GRADE not reported
OR 0.87 [0.31, 2.45]
1 study · 16 participants
GRADE not reported
Enamel remineralization extent · Human enamel specimens around orthodontic brackets (in vitro)
In vitro, a nano-CaF2-containing orthodontic cement showed significant enamel remineralization versus control in a single study (ungraded).
1 finding from 1 review
Intervention not reported
Pit-and-fissure caries progression (ICDAS), CO2 laser vs fluoride varnish alone
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD) changes change in probing depth (PD) (mm) compared with OFD (open flap debridement) alone (very low certainty).
1 finding from 1 review
Tooth survival · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review
Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + guided tissue regeneration… changes change in clinical attachment level (CAL) (mm) compared with GTR (guided tissue regeneration) alone (very low certainty).
3 findings from 1 review
MD 0.42 [-0.02, 0.86]
7 studies · 248 participants
Very low
MD 0.27 [-0.39, 0.93]
5 studies · 164 participants
GRADE not reported
MD 0.54 [0.18, 0.89]
3 studies · 134 participants
GRADE not reported
Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in clinical attachment level (CAL) (mm) compared with EMD (enamel matrix derivative) alone (very low certainty).
1 finding from 1 review
Pocket closure (complete pocket closure) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review
Oral health-related quality of life · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
The review found no eligible studies for this question.
1 finding from 1 review
Tooth survival · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review
Pocket closure (complete pocket closure) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review
Oral health-related quality of life · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
The review found no eligible studies for this question.
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + guided tissue regeneration… changes change in probing depth (PD) (mm) compared with GTR (guided tissue regeneration) alone (very low certainty).
3 findings from 1 review
MD 0.92 [-0.02, 1.86]
7 studies · 248 participants
Very low
MD 1.07 [-0.71, 2.86]
3 studies · 134 participants
GRADE not reported
MD 0.68 [-0.66, 2.02]
5 studies · 164 participants
GRADE not reported
Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in probing depth (PD) (mm) compared with EMD (enamel matrix derivative) alone (very low certainty).
1 finding from 1 review
Tooth survival · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review
Oral health-related quality of life · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
The review found no eligible studies for this question.
1 finding from 1 review
Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD) changes change in clinical attachment level (CAL) (mm) compared with OFD (open flap debridement) alone (very low certainty).
1 finding from 1 review