Participants with gametocytes at day 8, by microscopy · adults and children with malaria being treated with non‐artemisinin treatment
Single dose primaquine at 0.75 mg/kg probably leads to lower participants with gametocytes at day 8, by microscopy compared with no primaquine, with non‐artemisinin partner, (moderate certainty).
1 finding from 1 review
Participants with gametocytes at day 3‐4, by PCR · adults and children with malaria being treated with artemisinin combination treatment
Single dose primaquine at 0.2 to 0.25 mg/kg showed no clear difference in participants with gametocytes at day 3 to 4 by PCR compared with no primaquine, with artemisinin partner, (moderate certainty).
1 finding from 1 review
Participants with gametocytes at day 8, by PCR · adults and children with malaria being treated with artemisinin combination treatment
Single dose primaquine at 0.2 to 0.25 mg/kg leads to lower participants with gametocytes at day 8 by PCR compared with no primaquine, with artemisinin partner, (high certainty).
1 finding from 1 review
Participants infectious at day 8 · adults and children with malaria being treated with artemisinin combination treatment
Single dose primaquine at 0.4 to 0.5 mg/kg may leads to lower participants infectious at day 3‐4 compared with no primaquine, with artemisinin partner, (low certainty).
2 findings from 1 review
Participants with gametocytes at day 3‐4, by PCR · adults and children with malaria being treated with artemisinin combination treatment
Single dose primaquine at 0.4 to 0.5 mg/kg showed no clear difference in participants with gametocytes at day 3‐4, by PCR compared with no primaquine, with artemisinin partner, (moderate certainty).
1 finding from 1 review
Participants with gametocytes at day 8, by PCR · adults and children with malaria being treated with artemisinin combination treatment
Single dose primaquine at 0.4 to 0.5 mg/kg leads to lower participants with gametocytes at day 8, by PCR compared with no primaquine, with artemisinin partner, (high certainty).
1 finding from 1 review
Clinical resolution · acute infectious diarrhoea in children
Smectite may leads to higher clinical resolution at day 3 compared with control (low certainty).
1 finding from 1 review
Length of hospital stay · people diagnosed with suspected or confirmed Crimean Congo haemorrhagic fever
1 finding from 1 review
Intervention not reported
Diarrhoea on day 7 · children with persistent diarrhoea
The intervention showed no clear difference in diarrhoea on day 7 (low certainty).
1 finding from 1 review
Intervention not reported
Diarrhoea on day 7 · children with acute diarrhoea
The intervention probably leads to lower diarrhoea on day 7 (moderate certainty).
1 finding from 1 review
Intervention not reported
Diarrhoea on day 7 · children aged less than 6 months with acute diarrhoea
The intervention showed no clear difference in diarrhoea on day 7 (low certainty).
1 finding from 1 review
Treatment failure at day 28 · adults and children with uncomplicated P falciparum malaria
Artemisinin‐naphthoquine showed no clear difference in treatment failure at day 28 compared with AL (low certainty).
1 finding from 1 review
Treatment failure at day 42 · adults and children with uncomplicated P falciparum malaria
It is very uncertain whether artemisinin‐naphthoquine changes treatment failure at day 42 compared with AL (very low certainty).
1 finding from 1 review
Treatment failure at day 28 · adults and children with uncomplicated P falciparum malaria
1 finding from 1 review
Treatment failure at day 42 · adults and children with uncomplicated P falciparum malaria
It is very uncertain whether artemisinin‐naphthoquine changes treatment failure at day 42 compared with DHA‐P (very low certainty).
1 finding from 1 review
Intervention not reported
Days in hospital · Patients with dengue‐related shock
1 finding from 1 review
Intervention not reported
Patients still unwell at day 4 to 7 · People with fever
The intervention showed no clear difference in patients still unwell at day 4 to 7 (low certainty).
1 finding from 1 review
Treatment failure Day 28 · adults and children with uncomplicated P falciparum malaria
Dihydroartemisinin‐piperaquine leads to lower treatment failure Day 28 compared with artemether‐lumefantrine (high certainty).
1 finding from 1 review
Treatment failure Day 63 · adults and children with uncomplicated P falciparum malaria
Dihydroartemisinin‐piperaquine leads to lower treatment failure Day 63 compared with artemether‐lumefantrine (high certainty).
1 finding from 1 review
P. vivax parasitaemia detected > 30 days after starting primaquine · Children and adults with blood smear positive P. vivax malaria1
It is very uncertain whether primaquine (weekly for eight weeks) changes P. vivax parasitaemia detected > 30 days after starting primaquine compared with daily primaquine (very low certainty).
1 finding from 1 review