Mortality Mortality at latest · lung transplant recipients
Tacrolimus showed no clear difference in mortality Mortality at latest compared with cyclosporin (low certainty).
1 finding from 1 review
Acute rejection · lung transplant recipients
Tacrolimus showed no clear difference in acute rejection The number of patients who experienced at least one… compared with cyclosporin (low certainty).
1 finding from 1 review
Bronchiolitis obliterans syndrome · lung transplant recipients
Tacrolimus probably leads to lower bronchiolitis obliterans syndrome The number of patients diagnosed… compared with cyclosporin (moderate certainty).
1 finding from 1 review
Infection The number of overall infections per 100 patient days · lung transplant recipients
1 finding from 1 review
Treatment withdrawal · lung transplant recipients
Tacrolimus may leads to lower treatment withdrawal the number of patients stopping the assigned… compared with cyclosporin (low certainty).
1 finding from 1 review
Hypertension · lung transplant recipients
Tacrolimus may leads to lower arterial hypertension compared with cyclosporin (low certainty).
1 finding from 1 review
Diabetes · lung transplant recipients
Tacrolimus may leads to higher diabetes mellitus compared with cyclosporin (low certainty).
1 finding from 1 review
Disease‐specific mortality ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time to complete re‐epithelialisation ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Duration of ICU stay · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Length of hospital stay · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects leading to discontinuation of SJT/TEN therapy ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of participants achieving control of inflammation (higher number of events is better) · NIIPPU
It is very uncertain whether steroids with or without azathioprine changes proportion of participants achieving control of inflammation (higher… compared with cyclosporine A (very low certainty).
1 finding from 1 review
Change in BCVA (lower logMAR indicate better vision) · NIIPPU
1 finding from 1 review
Proportion of participants achieving a 2‐line improvement in visual acuity (Snellen chart) (higher scores indicate better vision) · NIIPPU
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of participants with confirmed macular edema (lower number of events is better) · NIIPPU
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of participants achieving steroid‐sparing control (higher number of events is better) · NIIPPU
It is very uncertain whether steroids with or without azathioprine changes proportion of participants achieving steroid‐sparing control (higher… compared with cyclosporine A (very low certainty).
1 finding from 1 review
Proportion of participants experiencing complications or requiring cessation of medication (lower number of events is better) · NIIPPU
It is very uncertain whether steroids with or without azathioprine changes proportion of participants experiencing complications or requiring… compared with cyclosporine A (very low certainty).
1 finding from 1 review
Change in TBUT (seconds) (longer is favored) · people with dry eye
Steroids showed no clear difference in change in TBUT (seconds) (longer is favored) compared with cyclosporine A (low certainty).
1 finding from 1 review
Change in fluorescein corneal staining scores (lower is favored) · people with dry eye
Steroids showed no clear difference in change in fluorescein corneal staining scores (lower is favored) compared with cyclosporine A (low certainty).
1 finding from 1 review