Findings

What do systematic reviews say?

92 questions · 92 findings · 7 reviews · Kidney and Transplant

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No studies found 20 · 21.7%GRADE not reported 3 · 3.3%Very low 33 · 35.9%Low 29 · 31.5%Moderate 7 · 7.6%High 0 · 0%

Summary of findings: Sevelamer vs calcium carbonate

Bone formation rate um(2)/mm(2)/d · patients with bone disease in children with chronic kidney disease

1 finding from 1 review

Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
Very low

Summary of findings: Sevelamer vs calcium carbonate

Fall in bone formation rate % · patients with bone disease in children with chronic kidney disease

1 finding from 1 review

Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
Very low

Summary of findings: Sevelamer vs calcium carbonate

PTH · patients with bone disease in children with chronic kidney disease

1 finding from 1 review

Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
Very low

Summary of findings: Sevelamer vs calcium carbonate

ALP U/L · patients with bone disease in children with chronic kidney disease

1 finding from 1 review

Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
Very low

Summary of findings: Sevelamer vs calcium carbonate

Serum phosphorus · patients with bone disease in children with chronic kidney disease

1 finding from 1 review

Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
Very low

Angiotensin‐converting enzyme inhibitors vs calcium channel blockers

Death · kidney transplant recipients

ACE Inhibitors showed no clear difference in death compared with calcium channel blockers (low certainty).

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
RR 4.03 [0.45, 35.82]
2 studies · 221 participants
Low

Angiotensin‐converting enzyme inhibitors vs calcium channel blockers

Graft loss · kidney transplant recipients

ACE Inhibitors showed no clear difference in graft loss compared with calcium channel blockers (low certainty).

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
RR 7.37 [0.39, 140.35]
1 study · 152 participants
Low

Angiotensin‐converting enzyme inhibitors vs calcium channel blockers

GFR · kidney transplant recipients

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 296 participants
Moderate

Angiotensin‐converting enzyme inhibitors vs calcium channel blockers

Acute rejection · kidney transplant recipients

It is very uncertain whether ACE Inhibitors changes acute rejection compared with calcium channel blockers (very low certainty).

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
RR 1.54 [1.14, 2.07]
2 studies · 221 participants
Very low

Angiotensin‐converting enzyme inhibitors vs calcium channel blockers

Proteinuria · kidney transplant recipients

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 142 participants
Moderate

Angiotensin‐converting enzyme inhibitors vs calcium channel blockers

Haemoglobin (g/dL) · kidney transplant recipients

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 332 participants
Moderate

Angiotensin‐converting enzyme inhibitors vs calcium channel blockers

Blood loss: post‐treatment haematocrit (%) · kidney transplant recipients

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 153 participants
Moderate