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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
2,434 questions in 139 reviews · Kidney and Transplant
current versionsNo studies 504 · 20.7%Ungraded 40 · 1.6%Very low 611 · 25.1%Low 790 · 32.5%Moderate 414 · 17%High 75 · 3.1%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Sevelamer vs calcium carbonate Bone formation rate um(2)/mm(2)/d · patients with bone disease in children with chronic kidney disease Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane | no estimate extracted | 1 study · 29 participants | Very low |
Sevelamer vs calcium carbonate Fall in bone formation rate % · patients with bone disease in children with chronic kidney disease Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane | no estimate extracted | 1 study · 29 participants | Very low |
Sevelamer vs calcium carbonate PTH pg/mL · patients with bone disease in children with chronic kidney disease Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane | no estimate extracted | 1 study · 29 participants | Very low |
Sevelamer vs calcium carbonate ALP U/L · patients with bone disease in children with chronic kidney disease Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane | no estimate extracted | 1 study · 29 participants | Very low |
Sevelamer vs calcium carbonate Calcium‐phosphorous product mg(2)/dL(2) · patients with bone disease in children with chronic kidney disease Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane | no estimate extracted | 1 study · 29 participants | Very low |
Sevelamer vs calcium carbonate Calcium mg/dL · patients with bone disease in children with chronic kidney disease Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane | no estimate extracted | 1 study · 29 participants | Very low |
Sevelamer vs calcium carbonate Phosphorus mg/dL · patients with bone disease in children with chronic kidney disease Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane | no estimate extracted | 1 study · 29 participants | Very low |
Intraperitoneal vs oral calcitriol PTH pg/mL · patients with bone disease in children with chronic kidney disease Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane | no estimate extracted | 1 study · 33 participants | Low |
Intraperitoneal vs oral calcitriol Adverse events ‐ Calcium > 11 mg/dL · patients with bone disease in children with chronic kidney disease Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane | no estimate extracted | 1 study · 33 participants | Low |
Intraperitoneal vs oral calcitriol Adverse events ‐ Phosphate > 7.0 mg/dL · patients with bone disease in children with chronic kidney disease Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane | no estimate extracted | 1 study · 33 participants | Low |
Intraperitoneal vs oral calcitriol Peritonitis episodes/patient‐months · patients with bone disease in children with chronic kidney disease Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane | no estimate extracted | 1 study · 21 participants | Low |
Intermittent oral vs daily oral calcitriol Change in height SDS · patients with bone disease in children with chronic kidney disease Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane | no estimate extracted | 1 study · 24 participants | Very low |
Intermittent oral vs daily oral calcitriol Fall in PTH % · patients with bone disease in children with chronic kidney disease Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane | no estimate extracted | 2 studies · 83 participants | Moderate |
Calcium channel blockers vs placebo/no treatment Death · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | RR 0.82 [0.37, 1.82] | 12 studies · 792 participants | Low |
ACE inhibitors vs placebo/no treatment GFR (measured or estimated) mL/min · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | no estimate extracted | 3 studies · 77 participants | Low |
ACE inhibitors vs placebo/no treatment Proteinuria g/24 h · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | no estimate extracted | 3 studies · 175 participants | Moderate |
ACE inhibitors vs placebo/no treatment Serum creatinine umol/L · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | no estimate extracted | 7 studies · 272 participants | Low |
ACE inhibitors vs placebo/no treatment Haemoglobin g/L · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | no estimate extracted | 5 studies · 191 participants | Moderate |
ACE inhibitors vs placebo/no treatment Blood pressure mmHg · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | no estimate extracted | 9 studies · 392 participants | Very low |
ACE Inhibitors vs calcium channel blockers Death · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | RR 4.03 [0.45, 35.82] | 2 studies · 221 participants | Low |
ACE Inhibitors vs calcium channel blockers Graft loss · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | RR 7.37 [0.39, 140.35] | 1 study · 152 participants | Low |
ACE Inhibitors vs calcium channel blockers GFR (measured or estimated) · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | no estimate extracted | 6 studies · 296 participants | Moderate |
ACE Inhibitors vs calcium channel blockers Acute rejection · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | RR 1.54 [1.14, 2.07] | 2 studies · 221 participants | Very low |
ACE Inhibitors vs calcium channel blockers Proteinuria g/24 h · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | no estimate extracted | 2 studies · 142 participants | Moderate |
Calcium channel blockers vs placebo/no treatment Graft loss · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | RR 0.75 [0.57, 0.99] | 17 studies · 1255 participants | Low |
ACE Inhibitors vs calcium channel blockers Haemoglobin g/L · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | no estimate extracted | 5 studies · 332 participants | Moderate |
ACE Inhibitors vs calcium channel blockers Haematocrit % · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | no estimate extracted | 4 studies · 153 participants | Moderate |
Calcium channel blockers vs placebo/no treatment GFR (measured or estimated) mL/min · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | no estimate extracted | 18 studies · 1119 participants | Moderate |
Calcium channel blockers vs placebo/no treatment Acute rejection · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | RR 1.02 [0.85, 1.23] | 11 studies · 771 participants | Low |
Calcium channel blockers vs placebo/no treatment Withdrawal due to side effects · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | RR 0.99 [0.53, 1.87] | 2 studies · 156 participants | Low |
Calcium channel blockers vs placebo/no treatment Proteinuria g/24 h · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | no estimate extracted | 2 studies · 90 participants | Low |
Calcium channel blockers vs placebo/no treatment Blood pressure mm Hg · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | no estimate extracted | 10 studies · 590 participants | Very low |
ACE inhibitors vs placebo/no treatment Death · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | RR 1 [0.07, 14.55] | 1 study · 30 participants | Low |
ACE inhibitors vs placebo/no treatment Graft loss · kidney transplant recipients Antihypertensive treatment for kidney transplant recipients (2009) · Cochrane | no estimate extracted | 2 studies · 93 participants | Low |