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Evidence found and GRADE certainty

1,338 questions · 2,104 findings · 136 reviews · Dental caries

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No studies found 159 · 7.6%GRADE not reported 1,657 · 78.8%Very low 138 · 6.6%Low 111 · 5.3%Moderate 36 · 1.7%High 3 · 0.1%

Compomer (Dyract) vs Amalgam (Tytin)

Secondary caries · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic or symptom free

Compomer (Dyract) showed no clear difference in secondary caries at 24 months compared with amalgam (Tytin); GRADE not reported.

1 finding from 1 review

Resin-modified glass ionomer (Vitremer) vs Amalgam restoration

Marginal integrity, wear, surface texture, staining and secondary caries (Ryge criteria) at 6-12 months · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic or symptom free
1 finding from 1 review
  • Dental fillings for the treatment of caries in the primary dentition 2009 · Cochrane All outcomes
    6-12 months
    Marginal integrity, wear, surface texture, axial contour, staining and secondary caries (Ryge criteria) at 6 and 12 months: odds ratios not estimable - no events recorded, implying equal performance of the two materials.
    1 study · 60 participants
    GRADE not reported

Fluoride toothpaste vs Fluoride mouthrinse

Proportion of children developing new caries (permanent) · Children and adolescents aged 16 years or less

Fluoride toothpaste showed no clear difference in proportion of children developing new caries (permanent) compared with fluoride mouthrinse; GRADE not reported.

1 finding from 1 review

Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Fluoride mouthrinse

Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review

Fluoride varnish vs Fluoride toothpaste alone

Proportion of children developing new caries (deciduous) · Children and adolescents aged 16 years or less
1 finding from 1 review

Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs Fluoride mouthrinse

Caries increment in permanent teeth · Children and adolescents aged 16 years or less
1 finding from 1 review

Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Fluoride toothpaste alone

Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review