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Evidence found and GRADE certainty

1,733 questions · 1,794 findings · 326 reviews · Headline outcomes only

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No studies found 243 · 13.5%GRADE not reported 96 · 5.4%Very low 597 · 33.3%Low 506 · 28.2%Moderate 303 · 16.9%High 49 · 2.7%

Relaxation vs usual care

Pain as assessed post‐intervention Short Form ‐ McGill Pain Questionnaire Total Score. Scale from: 0 to 78 · patients with fibromyalgia
1 finding from 1 review

PERPHENAZINE vs placebo

Global state: Change over time ‐ no better or deterioration ‐ short term clinically defined · patients with schizophrenia

It is very uncertain whether PERPHENAZINE changes global state: Change over time ‐ no better or deterioration ‐ short… compared with PLACEBO (very low certainty).

1 finding from 1 review

PERPHENAZINE vs antipsychotics

Adverse events: extrapyramidal adverse effects ‐ dystonia ‐ short term · patients with schizophrenia

It is very uncertain whether PERPHENAZINE changes adverse events: extrapyramidal adverse effects dystonia ‐ short term compared with ANY ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

PERPHENAZINE vs antipsychotics

Other adverse events: any serious adverse event ‐ short and long term · patients with schizophrenia

It is very uncertain whether PERPHENAZINE changes other adverse events: any serious adverse event ‐ short and long term compared with ANY ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

PERPHENAZINE vs placebo

Relapse · patients with schizophrenia

It is very uncertain whether PERPHENAZINE changes mental state: Relapse ‐ short term clinical diagnosis compared with PLACEBO (very low certainty).

1 finding from 1 review

PERPHENAZINE vs placebo

Adverse events: extrapyramidal adverse effects ‐ dystonia ‐ short term · patients with schizophrenia

It is very uncertain whether PERPHENAZINE changes adverse events: extrapyramidal adverse effects ‐ dystonia ‐ short term compared with PLACEBO (very low certainty).

1 finding from 1 review

PERPHENAZINE vs antipsychotics

Global state: Change over time ‐ no better or deterioration ‐ short and medium term as defined in each study · patients with schizophrenia

It is very uncertain whether PERPHENAZINE changes global state: Change over time ‐ no better or deterioration ‐ short… compared with ANY ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

Manipulation (thoracic) vs inactive control

Acute and subacute neck pain Short‐term · patients with acute, subacute and chronic neck pain

Manipulation (thoracic) showed no clear difference in acute and subacute neck pain Short‐term compared with inactive control (moderate certainty).

1 finding from 1 review

Intervention not reported

Short‐term neurological sequelae · acute bacterial meningitis

The intervention showed no clear difference in short‐term neurological sequelae (high certainty).

1 finding from 1 review

Chondroitin vs placebo

Pain on a 0 to 100 mm scale ‐ Short‐term studies (< 6 months)—dose ≥ 800 mg/d · patients with osteoarthritis
1 finding from 1 review