Findings

What do systematic reviews say?

1,935 questions · 1,986 findings · 260 reviews · Headline outcomes only

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No studies found 503 · 25.3%GRADE not reported 76 · 3.8%Very low 593 · 29.9%Low 509 · 25.6%Moderate 241 · 12.1%High 64 · 3.2%

Intervention not reported

Dexamethasone (1 RCT; 149 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 149 participants
Very low

Intervention not reported

Methylprednisolone (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Dexamethasone (3 RCTs; 376 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 376 participants
Very low

Intervention not reported

Methylprednisolone (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Dexamethasone (6 RCTs; 1152 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1152 participants
Low

Intervention not reported

Methylprednisolone (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Vitamin D vs placebo or no intervention

Adverse effect: kidney stonesb · children under 5 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Effects of oral vitamin D supplementation on linear growth and other health outcomes among children under five years… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Mifepristone (all doses) vs Yuzpe

Observed number of pregnancies (all women) · women seeking emergency contraception

Mifepristone (all doses) leads to lower observed number of pregnancies (all women) compared with yuzpe (high certainty).

1 finding from 1 review

Interventions for emergency contraception 2019 · Cochrane Headline outcomes only
RR 0.14 [0.05, 0.41]
3 studies · 2144 participants
High

Mifepristone (all doses) vs Yuzpe

Side effects · women seeking emergency contraception

Mifepristone (all doses) probably leads to lower any side effect compared with yuzpe (moderate certainty).

1 finding from 1 review

Interventions for emergency contraception 2019 · Cochrane Headline outcomes only
RR 0.83 [0.77, 0.88]
2 studies · 1693 participants
Moderate

Mifepristone (all doses) vs Yuzpe

Nausea · women seeking emergency contraception

Mifepristone (all doses) probably leads to lower specific side effects ‐ nausea compared with yuzpe (moderate certainty).

1 finding from 1 review

Interventions for emergency contraception 2019 · Cochrane Headline outcomes only
RR 0.63 [0.53, 0.76]
3 studies · 2186 participants
Moderate

Mifepristone (all doses) vs Yuzpe

Vomiting · women seeking emergency contraception

Mifepristone (all doses) leads to lower specific side effects ‐ vomiting compared with yuzpe (high certainty).

1 finding from 1 review

Interventions for emergency contraception 2019 · Cochrane Headline outcomes only
RR 0.12 [0.07, 0.2]
3 studies · 2186 participants
High

Mifepristone (all doses) vs Yuzpe

Abdominal pain · women seeking emergency contraception

Mifepristone (all doses) probably leads to lower specific side effects ‐ abdominal pain compared with yuzpe (moderate certainty).

1 finding from 1 review

Interventions for emergency contraception 2019 · Cochrane Headline outcomes only
RR 0.76 [0.61, 0.95]
1 study · 1000 participants
Moderate

Mifepristone (all doses) vs Yuzpe

Specific side effects ‐ spotting/bleeding after treatment · women seeking emergency contraception

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for emergency contraception 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Mifepristone (all doses) vs Yuzpe

Menses ‐ delay · women seeking emergency contraception

Mifepristone (all doses) probably leads to higher menses ‐ delay compared with yuzpe (moderate certainty).

1 finding from 1 review

Interventions for emergency contraception 2019 · Cochrane Headline outcomes only
RR 2.83 [2.3, 3.47]
3 studies · 1924 participants
Moderate

Antibiotics vs no intervention

Serological cure (4‐fold decrease or greater in non‐treponemal tests titre) · newborns with congenital syphilis

Antibiotic treatment may leads to higher serological cure (≥ 4‐fold decrease in non‐treponemal tests titre) compared with no intervention (low certainty).

1 finding from 1 review

Antibiotic treatment for newborns with congenital syphilis 2019 · Cochrane Headline outcomes only
RR 2.13 [1.06, 4.27]
1 study · 20 participants
Low

Fexofenadine 120 mg/d vs placebo (1‐week intervention)

Secondary outcome 3. Number of eczema flares, measured by, for example, ‘escalation of treatment’ or ‘use of topical anti‐inflammatory medications’ Amount of 0.1% hydrocortisone butyrate cream used during the study · adults with eczema

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Moderate

Eplerenone (25 mg daily) vs placebo

Change in cardiac function: change (decline) from baseline in left ventricular strain · boys with DMD and left ventricular ejection fraction 45% or more

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Very low

Eplerenone (25 mg daily) vs placebo

Change in Ejection fraction (%) · boys with DMD and left ventricular ejection fraction 45% or more

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Very low

Eplerenone (25 mg daily) vs placebo

Size of metabolically abnormal areas of myocardium · boys with DMD and left ventricular ejection fraction 45% or more

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Low

Eplerenone (25 mg daily) vs placebo

Improvements in quality of life measures · boys with DMD and left ventricular ejection fraction 45% or more

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found