Findings

What do systematic reviews say?

4,749 questions · 14,261 findings · 832 reviews

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No studies found 3,655 · 25.6%GRADE not reported 2,111 · 14.8%Very low 3,646 · 25.6%Low 3,028 · 21.2%Moderate 1,501 · 10.5%High 320 · 2.2%

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Topical mydriatics vs intracameral mydriatics

Mean pupillary diameter—at the time the surgeon performs capsulorhexis (mm) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 757 participants
Low

Topical mydriatics vs depot delivery systems

Mean pupillary diameter—at the time the surgeon performs capsulorhexis (mm) · patients undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical mydriatics vs depot delivery systems

AE: participant‐reported ocular discomfort—week 1 · patients undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical mydriatics vs depot delivery systems

AE: participant‐reported ocular discomfort—month 1 · patients undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intracameral mydriatics vs depot delivery systems

Mean pupillary diameter—at the time the surgeon performs capsulorhexis (mm) · patients undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intracameral mydriatics vs depot delivery systems

AE: participant‐reported ocular discomfort—week 1 · patients undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intracameral mydriatics vs depot delivery systems

AE: participant‐reported ocular discomfort—month 1 · patients undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical mydriatics vs intracameral mydriatics

Total time it took for the surgeon to perform phacoemulsification (seconds) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 48 participants
Very low

Topical mydriatics vs intracameral mydriatics

AE: participant‐reported ocular discomfort—week 1 · patients undergoing cataract surgery

It is very uncertain whether topical mydriatics changes AE: participant‐reported ocular discomfort—week 1 compared with intracameral mydriatics (very low certainty).

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 10.57 [1.37, 81.34]
1 study · 555 participants
Very low

Topical mydriatics vs intracameral mydriatics

AE: participant‐reported ocular discomfort—month 1 · patients undergoing cataract surgery

Topical mydriatics probably leads to higher AE: participant‐reported ocular discomfort—month 1 compared with intracameral mydriatics (moderate certainty).

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 2.51 [1.36, 4.65]
1 study · 543 participants
Moderate

Eculizumab vs placebo or alternative treatment

Requirement for KRT · children and adults with aHUS

1 finding from 1 review

Interventions for atypical haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
100 participants
Very low

Ravulizumab vs placebo or alternative treatment

Requirement for KRT · adults with aHUS

1 finding from 1 review

Interventions for atypical haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
56 participants
Very low

Synsorb Pk vs placebo

Need for acute dialysis · patients with diarrhoea due to Shiga toxin‐producing E. coli

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing diarrhoea‐associated haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Urtoxazumab (3.0 mg/kg) vs placebo

Need for acute dialysis · paediatric patients with diarrhoea due to Shiga toxin‐producing E. coli

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing diarrhoea‐associated haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Urtoxazumab (1.0 mg/kg) vs placebo

Need for acute dialysis · paediatric patients with diarrhoea due to Shiga toxin‐producing E. coli

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing diarrhoea‐associated haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment

Need for acute dialysis · patients with diarrhoea due to Shiga toxin‐producing E. coli

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing diarrhoea‐associated haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Bovine colostrum vs placebo

Need for acute dialysis · patients with diarrhoea due to Shiga toxin‐producing E. coli

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing diarrhoea‐associated haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

Change in intensity of the nystagmus waveform · infantile nystagmus syndrome

1 finding from 1 review

Surgical interventions for infantile nystagmus syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 10 participants
Very low

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

Change in foveation period durations of the waveform ‐ not reported · infantile nystagmus syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Surgical interventions for infantile nystagmus syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Mindfulness vs no treatment or waiting list

Academic achievement (

1 finding from 1 review

Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior doctors 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 79 participants
Very low