Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,773 questions · 1,817 findings · 212 reviews · Headline outcomes only

No studies found 383 · 21.1%GRADE not reported 192 · 10.6%Very low 472 · 26%Low 444 · 24.4%Moderate 228 · 12.5%High 98 · 5.4%

Propofol vs sevoflurane

Adverse event ‐ haemodynamic changes, number of events · patients with rapid emergence from anaesthesia after undergoing brain tumour surgery

Propofol may leads to higher adverse event ‐ haemodynamic changes, number of events compared with sevoflurane (low certainty).

1 finding from 1 review

Propofol vs sevoflurane

Adverse event ‐ pain, visual analogue scale · patients with rapid emergence from anaesthesia after undergoing brain tumour surgery

Propofol showed no clear difference in adverse event ‐ pain, visual analogue scale compared with sevoflurane (low certainty).

1 finding from 1 review

Mobile bearing vs fixed bearing prosthesis

Knee pain Knee Society Score, sub score pain (possible range 0 (severe pain) ‐ 50 (no pain) points) · patients with posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients with osteoarthritis and…
1 finding from 1 review

Mobile bearing vs fixed bearing prosthesis

Function ‐ measured as KSS function Knee Society Score, function. Scale from 0 to 100 (higher scores indicates better function) · patients with posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients with osteoarthritis and…
1 finding from 1 review

Mobile bearing vs fixed bearing prosthesis

Revision surgery · patients with posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients with osteoarthritis and…

Mobile bearing may leads to lower revision surgery compared with fixed bearing prosthesis (low certainty).

1 finding from 1 review

Mobile bearing vs fixed bearing prosthesis

All‐cause mortality · patients with posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients with osteoarthritis and…

Mobile bearing may leads to lower mortality compared with fixed bearing prosthesis (low certainty).

1 finding from 1 review

Mobile bearing vs fixed bearing prosthesis

Reoperation rate · patients with posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients with osteoarthritis and…

Mobile bearing may leads to higher reoperation rate compared with fixed bearing prosthesis (low certainty).

1 finding from 1 review

Mobile bearing vs fixed bearing prosthesis

Other serious adverse events · patients with posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients with osteoarthritis and…

Mobile bearing may leads to higher other serious adverse events compared with fixed bearing prosthesis (low certainty).

1 finding from 1 review

Regional (spinal, epidural, caudal) vs general anaesthesia

Apnoea/bradycardia occurring 12‐24 hours following completion of operation · Preterm infants requiring surgery for inguinal hernia in early infancy

Regional (spinal, epidural, caudal) showed no clear difference in apnoea/bradycardia occurring 12‐24 hours following completion of… compared with general anaesthesia (moderate certainty).

1 finding from 1 review

Regional (spinal, epidural, caudal) vs general anaesthesia

Any oxygen desaturation occurring 12‐24 hours following completion of the operation · Preterm infants requiring surgery for inguinal hernia in early infancy

Regional (spinal, epidural, caudal) showed no clear difference in any oxygen desaturation occurring 12‐24 hours following completion… compared with general anaesthesia (moderate certainty).

1 finding from 1 review

Regional (spinal, epidural, caudal) vs general anaesthesia

Use of post‐operative respiratory support · Preterm infants requiring surgery for inguinal hernia in early infancy

Regional (spinal, epidural, caudal) showed no clear difference in use of post‐operative respiratory support compared with general anaesthesia (low certainty).

1 finding from 1 review

Regional (spinal, epidural, caudal) vs general anaesthesia

Post‐operative apnoea with preoperative sedatives excluded · Preterm infants requiring surgery for inguinal hernia in early infancy

Regional (spinal, epidural, caudal) probably leads to lower post‐operative apnoea with preoperative sedatives excluded compared with general anaesthesia (moderate certainty).

1 finding from 1 review

Regional (spinal, epidural, caudal) vs general anaesthesia

Anaesthetic agent failure · Preterm infants requiring surgery for inguinal hernia in early infancy

Regional (spinal, epidural, caudal) may leads to higher anaesthetic agent failure compared with general anaesthesia (low certainty).

1 finding from 1 review

Regional (spinal, epidural, caudal) vs general anaesthesia

Anaesthetic placement failure · Preterm infants requiring surgery for inguinal hernia in early infancy

Regional (spinal, epidural, caudal) showed no clear difference in anaesthetic placement failure compared with general anaesthesia (low certainty).

1 finding from 1 review