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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
2,653 questions in 194 reviews · Gynaecology and Fertility
current versionsNo studies 531 · 20%Ungraded 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Progesterone vs progesterone + oestrogen Live birth or ongoing pregnancy · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 1.12 [0.91, 1.38] | 9 studies · 1651 participants | Low |
Progesterone vs progesterone + oestrogen Clinical pregnancy · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 0.86 [0.72, 1.04] | 14 studies · 2169 participants | Low |
Progesterone vs progesterone + oestrogen OHSS · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 0.58 [0.2, 1.68] | 2 studies · 461 participants | Low |
Progesterone vs progesterone + GnRH agonist Live birth or ongoing pregnancy · women who had undergone IVF/ICSI Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 0.62 [0.48, 0.81] | 9 studies · 2861 participants | Very low |
Progesterone vs progesterone + GnRH agonist Clinical pregnancy · women who had undergone IVF/ICSI Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 0.66 [0.51, 0.85] | 8 studies · 2435 participants | Low |
Progesterone vs progesterone + GnRH agonist OHSS · women who had undergone IVF/ICSI Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 1 [0.33, 3.01] | 1 study · 300 participants | Very low |
Intervention NR Live birth or ongoing pregnancy IM vs oral · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 0.71 [0.14, 3.66] | 1 study · 40 participants | Very low |
Intervention NR Live birth or ongoing pregnancy IM vs vaginal/rectal · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 1.24 [1.03, 1.5] | 7 studies · 2309 participants | Very low |
Intervention NR Live birth or ongoing pregnancy Vaginal/rectal vs oral · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 1.19 [0.83, 1.69] | 4 studies · 857 participants | Low |
Intervention NR Live birth or ongoing pregnancy Low dose vaginal vs high dose vaginal · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 0.97 [0.84, 1.11] | 5 studies · 3720 participants | Moderate |
hCG vs placebo/no treatment Clinical pregnancy · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 1.3 [0.9, 1.88] | 5 studies · 746 participants | Very low |
Intervention NR Live birth or ongoing pregnancy Short protocol vs long protocol · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 1.04 [0.79, 1.36] | 5 studies · 1205 participants | Low |
Intervention NR Live birth or ongoing pregnancy Micronised vs synthetic · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 0.9 [0.53, 1.55] | 2 studies · 470 participants | Low |
Intervention NR Live birth or ongoing pregnancy Vaginal ring vs vaginal gel · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 1.09 [0.88, 1.36] | 1 study · 1271 participants | Low |
Intervention NR Live birth or ongoing pregnancy Subcutaneous vs vaginal gel · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 0.92 [0.74, 1.14] | 2 studies · 1465 participants | Low |
Intervention NR Live birth or ongoing pregnancy Vaginal vs rectal · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 1.28 [0.64, 2.54] | 1 study · 147 participants | Very low |
Intervention NR OHSS IM vs oral · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 1 [0.06, 17.18] | 1 study · 40 participants | Very low |
Intervention NR OHSS Low dose vaginal vs high dose vaginal · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 0.91 [0.57, 1.46] | 2 studies · 1251 participants | Low |
Intervention NR Live birth/ongoing pregnancy ‐ short vs long protocol · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 1.08 [0.81, 1.43] | 1 study · 910 participants | Low |
Intervention NR Live birth/ongoing pregnancy ‐ low vs high dose protocol · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 0.65 [0.37, 1.13] | 1 study · 285 participants | Very low |
Intervention NR OHSS ‐ short vs long protocol · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | no estimate extracted | NR | No studies |
hCG vs placebo/no treatment OHSS · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 4.28 [1.91, 9.6] | 1 study · 387 participants | Low |
Intervention NR OHSS ‐ low vs high dose protocol · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | no estimate extracted | NR | No studies |
Progesterone vs placebo/no treatment Live birth or ongoing pregnancy · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 1.77 [1.09, 2.86] | 5 studies · 642 participants | Very low |
Progesterone vs placebo/no treatment Clinical pregnancy · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 1.89 [1.3, 2.75] | 7 studies · 841 participants | Low |
Progesterone vs placebo/no treatment OHSS · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | no estimate extracted | NR | No studies |
Progesterone vs hCG regimens Live birth or ongoing pregnancy · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 0.95 [0.65, 1.38] | 5 studies · 833 participants | Low |
Progesterone vs hCG regimens Clinical pregnancy · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 1.08 [0.9, 1.3] | 16 studies · 2355 participants | Moderate |
Progesterone vs hCG regimens OHSS · subfertile women Luteal phase support for assisted reproduction cycles (2015) · Cochrane | OR 0.46 [0.3, 0.71] | 5 studies · 1293 participants | Low |
Long‐acting FSH (all doses) vs daily FSH Live birth rate ‐ Low dose (60 to 120 μg) Long‐acting FSH versus daily FSH for women undergoing assisted reproduction (2015) · Cochrane | RR 0.7 [0.52, 0.93] | 3 studies · 645 participants | Moderate |
Long‐acting FSH (all doses) vs daily FSH Live birth rate ‐ Medium dose (150 to 180 μg) Long‐acting FSH versus daily FSH for women undergoing assisted reproduction (2015) · Cochrane | RR 1.03 [0.9, 1.18] | 4 studies · 1685 participants | Moderate |
Long‐acting FSH (all doses) vs daily FSH Live birth rate ‐ High dose (240 μg) Long‐acting FSH versus daily FSH for women undergoing assisted reproduction (2015) · Cochrane | RR 0.43 [0.12, 1.52] | 1 study · 33 participants | Very low |
Long‐acting FSH (all doses) vs daily FSH OHSS ‐ Low dose (60 to 120 μg) Long‐acting FSH versus daily FSH for women undergoing assisted reproduction (2015) · Cochrane | RR 1.22 [0.56, 2.66] | 3 studies · 645 participants | Moderate |
Long‐acting FSH (all doses) vs daily FSH OHSS ‐ Medium dose (150 to 180 μg) Long‐acting FSH versus daily FSH for women undergoing assisted reproduction (2015) · Cochrane | RR 0.96 [0.68, 1.35] | 5 studies · 3075 participants | Low |
Long‐acting FSH (all doses) vs daily FSH OHSS ‐ High dose (240 μg) Long‐acting FSH versus daily FSH for women undergoing assisted reproduction (2015) · Cochrane | RR 1.73 [0.09, 32.75] | 1 study · 33 participants | Very low |
DHEA or testosterone vs placebo/no treatment Live birth/ongoing pregnancy rate ‐ DHEA · Women undergoing assisted reproduction Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction (2015) · Cochrane | OR 1.81 [1.25, 2.62] | 8 studies · 878 participants | Moderate |
Testosterone vs other active interventions Live birth ‐ Testosterone vs estradiol + OCP · Women undergoing assisted reproduction Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction (2015) · Cochrane | OR 1.67 [0.34, 8.1] | 1 study · 42 participants | Very low |
Testosterone vs other active interventions Miscarriage ‐ Testosterone vs estradiol · Women undergoing assisted reproduction Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction (2015) · Cochrane | OR 0.7 [0.11, 4.64] | 1 study · 46 participants | Very low |
Testosterone vs other active interventions Miscarriage ‐ Testosterone vs estradiol + OCP · Women undergoing assisted reproduction Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction (2015) · Cochrane | OR 1.9 [0.16, 22.72] | 1 study · 42 participants | Very low |
Testosterone vs other active interventions Clinical pregnancy rate ‐ Testosterone vs estradiol · Women undergoing assisted reproduction Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction (2015) · Cochrane | OR 1.4 [0.39, 5.07] | 1 study · 46 participants | Very low |
Testosterone vs other active interventions Clinical pregnancy rate ‐ Testosterone vs estradiol + OCP · Women undergoing assisted reproduction Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction (2015) · Cochrane | OR 1.87 [0.45, 7.69] | 1 study · 42 participants | Very low |
DHEA or testosterone vs placebo/no treatment Live birth/ongoing pregnancy rate ‐ Testosterone · Women undergoing assisted reproduction Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction (2015) · Cochrane | OR 2.6 [1.3, 5.2] | 4 studies · 345 participants | Moderate |
DHEA or testosterone vs placebo/no treatment Miscarriage rate ‐ DHEA · Women undergoing assisted reproduction Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction (2015) · Cochrane | OR 0.58 [0.29, 1.17] | 8 studies · 950 participants | Moderate |
DHEA or testosterone vs placebo/no treatment Miscarriage rate ‐ Testosterone · Women undergoing assisted reproduction Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction (2015) · Cochrane | OR 2.04 [0.58, 7.13] | 4 studies · 345 participants | Low |
DHEA or testosterone vs placebo/no treatment Clinical pregnancy rate ‐ DHEA · Women undergoing assisted reproduction Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction (2015) · Cochrane | OR 1.34 [1.01, 1.76] | 12 studies · 1246 participants | Moderate |
DHEA or testosterone vs placebo/no treatment Clinical pregnancy rate ‐ Testosterone · Women undergoing assisted reproduction Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction (2015) · Cochrane | OR 2.52 [1.36, 4.68] | 4 studies · 345 participants | Moderate |
DHEA or testosterone vs placebo/no treatment Multiple pregnancy ‐ DHEA · Women undergoing assisted reproduction Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction (2015) · Cochrane | OR 3.23 [0.13, 81.01] | 5 studies · 267 participants | Very low |
DHEA or testosterone vs placebo/no treatment Multiple pregnancy ‐ Testosterone · Women undergoing assisted reproduction Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction (2015) · Cochrane | OR 3.09 [0.48, 19.98] | 3 studies · 292 participants | Very low |
Testosterone vs other active interventions Live birth ‐ Testosterone vs estradiol · Women undergoing assisted reproduction Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction (2015) · Cochrane | OR 2.06 [0.43, 9.87] | 1 study · 46 participants | Very low |
Radially expanding trocars vs cutting trocars Visceral injury · people undergoing laparoscopy Trocar types in laparoscopy (2015) · Cochrane | OR 0.95 [0.06, 15.32] | 4 studies · 473 participants | Very low |