Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,736 questions · 15,265 findings · 1,163 reviews · Headline outcomes only

No studies found 3,871 · 25.4%GRADE not reported 810 · 5.3%Very low 4,242 · 27.8%Low 3,879 · 25.4%Moderate 1,999 · 13.1%High 464 · 3%

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Parenting‐focused psychosocial interventions WITHOUT substance use‐focused component vs treatment

Frequency of drug use 12 months · Parents who use substances
2 findings from 1 review

Upper limb exercise training vs control (no intervention/usual care/isotonic exercise)

Ultrasound maturation (isotonic exercise training versus no intervention) · CKD patients who underwent AVF creation

Upper limb exercise training showed no clear difference in ultrasound maturation (isotonic exercise training versus no… compared with control (no intervention/usual care/isotonic exercise) (low certainty).

1 finding from 1 review

Upper limb exercise training vs control (no intervention/usual care/isotonic exercise)

Clinical maturation (isotonic exercise training versus no intervention) · CKD patients who underwent AVF creation

Upper limb exercise training may leads to higher clinical maturation (isotonic exercise training versus no… compared with control (no intervention/usual care/isotonic exercise) (low certainty).

1 finding from 1 review

Intervention not reported

All intervention options · people with first recurrence of glioblastoma Interventions: bevacizumab (BEV), BEV + lomustine (LOM), regorafenib (REG), fotemustine…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

All intervention options · people with first recurrence of glioblastoma Interventions: bevacizumab (BEV), BEV + lomustine (LOM), regorafenib (REG), BEV + irinotecan…

The review found no eligible studies for this question.

1 finding from 1 review