Bisphosphonates vs placebo
The review found no eligible studies for this question.
- Bisphosphonates for osteoporosis in people with cystic fibrosis 2023 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
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The review found no eligible studies for this question.
The review found no eligible studies for this question.
Bisphosphonates showed no clear difference in new vertebral fractures compared with placebo (low certainty).
Bisphosphonates showed no clear difference in new non‐vertebral fractures compared with placebo (low certainty).
Combined OCP may leads to higher pain improvement (assessed as improvement from 1 major category to… compared with placebo or no treatment (low certainty).
Combined OCP probably leads to higher adverse events compared with placebo or no treatment (moderate certainty).
Combined OCP may leads to lower requirement for additional medication compared with placebo or no treatment (low certainty).
Combined OCP may leads to lower absence from work or school compared with placebo or no treatment (low certainty).
It is very uncertain whether pharmacological interventions changes depression: meeting study criteria for depression at end of… compared with placebo (very low certainty).
It is very uncertain whether pharmacological interventions changes depression: < 50% reduction in scale scores at end of treatment… compared with placebo (very low certainty).
It is very uncertain whether pharmacological interventions changes adverse events: death (secondary outcome) compared with placebo (very low certainty).
It is very uncertain whether pharmacological interventions changes adverse events: all ‐ central nervous system events (e.g. confusion,… compared with placebo (very low certainty).
It is very uncertain whether pharmacological interventions changes adverse events: all ‐ gastrointestinal effects (e.g. constipation,… compared with placebo (very low certainty).
Corticosteroids may leads to higher clinical improvement (dichotomous) compared with placebo (low certainty).