Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,006 questions · 3,171 findings · 607 reviews · Headline outcomes only

No studies found 411 · 13%GRADE not reported 153 · 4.8%Very low 968 · 30.5%Low 897 · 28.3%Moderate 589 · 18.6%High 153 · 4.8%

Summary of findings table ‐ Progestogens vs GnRH antagonists

Duration of stimulation (days) ‐ PCOS (high‐responders) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles
1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH antagonists

Total dose of gonadotropins (IU) ‐ PCOS (high‐responders) ‐ Own oocytes ‐ Early phase stumulation protocol ‐ Frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles
1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH antagonists

Live birth or ongoing pregnancy sensitivity analysis ‐ PCOS (high‐responders) ‐ own oocytes ‐ early phase stimulation protocol ‐ frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles

Summary of findings table ‐ Progestogens showed no clear difference in live birth or ongoing pregnancy sensitivity analysis ‐ PCOS… compared with gnRH antagonists; GRADE not reported.

1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH antagonists

Oocyte pick‐up cancellation sensitivity analysis ‐ PCOS (high‐responders)(micronised progesterone 100 mg versus GnRH antagonists) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Frozen embryo transfer · assisted reproduction technology cycles

Summary of findings table ‐ Progestogens showed no clear difference in oocyte pick‐up cancellation sensitivity analysis ‐ PCOS… compared with gnRH antagonists; GRADE not reported.

1 finding from 1 review

CBT vs TAU

Functional disability (Higher scores indicate higher levels of disability) · chronic pain (excluding headache) in adults
2 findings from 1 review

CBT vs TAU

Quality of life (Higher scores indicate improvement) · chronic pain (excluding headache) in adults
2 findings from 1 review

CBT vs active control

Functional disability at 3 months ‐ not measured · chronic pain (excluding headache) in adults
2 findings from 1 review

CBT vs active control

Quality of life (Higher scores indicate improvement) · chronic pain (excluding headache) in adults
2 findings from 1 review

CBT vs TAU

Pain intensity (number of people with ≥ 30% improvement) (Higher scores indicate improvement) · chronic pain (excluding headache) in adults

CBT probably leads to higher pain intensity (number of people with ≥ 30% improvement) (Higher… compared with TAU (post‐treatment) (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Selective prevention interventions vs control group

Depressive symptoms · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Selective prevention interventions vs control group

Distress/PTSD symptoms at study endpoint (higher score = higher severity) · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

QoL · preventing mental disorders
2 findings from 1 review

Summary of findings table ‐ Indicated prevention interventions vs control group

Psychological functioning and impairment at study endpoint (higher score = higher disability) · preventing mental disorders
2 findings from 1 review