Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,539 questions · 2,602 findings · 424 reviews · Headline outcomes only

No studies found 572 · 22%GRADE not reported 189 · 7.3%Very low 527 · 20.3%Low 685 · 26.3%Moderate 514 · 19.8%High 115 · 4.4%

Imiquimod vs vehicle

Long‐term clinical cure (beyond 6 months after start of treatment) (completely cleared long term) · molluscum contagiosum

Imiquimod showed no clear difference in long‐term clinical cure (beyond 6 months after start of treatment)… compared with vehicle (moderate certainty).

1 finding from 1 review

CLOZAPINE + RISPERIDONE vs CLOZAPINE + ZIPRASIDONE (Kuwilsky 2010)

Acceptability of treatment ‐ leaving the study early · people with treatment‐resistant schizophrenia

It is very uncertain whether CLOZAPINE + RISPERIDONE changes leaving the study early: acceptability of treatment ‐ as measured by… compared with CLOZAPINE + ZIPRASIDONE (Kuwilsky 2010) (very low certainty).

1 finding from 1 review

CLOZAPINE + ARIPIPRAZOLE vs CLOZAPINE + HALOPERIDOL (Cipriani 2013)

Acceptability of treatment ‐ leaving the study early · people with treatment‐resistant schizophrenia

It is very uncertain whether CLOZAPINE + ARIPIPRAZOLE changes leaving the study early: acceptability of treatment ‐ as measured by… compared with CLOZAPINE + HALOPERIDOL (Cipriani 2013) (very low certainty).

1 finding from 1 review

Retroperitoneal drainage vs no drainage after pelvic lymphadenectomy

Long‐term lymphocyst formation: both asymptomatic and symptomatic at 12 months after surgery · patients with gynaecological malignancies

Retroperitoneal drainage showed no clear difference in long‐term lymphocyst formation: both asymptomatic and symptomatic at… compared with no drainage after pelvic lymphadenectomy (high certainty).

1 finding from 1 review

Retroperitoneal drainage vs no drainage after pelvic lymphadenectomy

Long‐term lymphocyst formation: symptomatic at 12 months after surgery · patients with gynaecological malignancies

Retroperitoneal drainage showed no clear difference in long‐term lymphocyst formation: symptomatic at 12 months after surgery compared with no drainage after pelvic lymphadenectomy (low certainty).

1 finding from 1 review