Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,171 questions · 1,373 findings · 60 reviews · Dental caries

No studies found 282 · 20.5%GRADE not reported 606 · 44.1%Very low 257 · 18.7%Low 160 · 11.7%Moderate 66 · 4.8%High 2 · 0.1%

Metal-free implant abutments (zirconia) vs Metal implant abutments (titanium)

Aesthetics · Adults (18 years or older) with one missing tooth in the aesthetic zone needing an implant-supported single crown
1 finding from 1 review
  • Primary outcome aesthetic evaluation data were reported as the frequency of distribution of the Implant Crown Aesthetic Index (ICAI); no comparative summary estimate was presented.
    2 studies · 47 participants
    Very low

Metal-free cantilevered FDPs (feldspathic-veneered zirconia) vs Metal-ceramic cantilevered FDPs

Aesthetics evaluated by the patient · Adults (18 years or older) needing replacement of one premolar or incisor with a cantilevered fixed dental prosthesis

It is very uncertain whether metal-free cantilevered FDPs (feldspathic-veneered zirconia) changes aesthetic evaluation (patient VAS) compared with metal-ceramic cantilevered FDPs (very low certainty).

1 finding from 1 review

ART using resin-modified glass ionomer cement (RM-GIC) vs Conventional treatment using RM-GIC

Restoration failure (permanent, mature dentition; root surfaces) · Older adults with root caries in permanent (mature) teeth (mean age 75 years)

It is very uncertain whether ART using resin-modified glass ionomer cement (RM-GIC) changes restoration failure (permanent, mature dentition; root surfaces) compared with conventional treatment using RM-GIC (very low certainty).

1 finding from 1 review

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Marginal deterioration of the restoration and fracture of the remaining tooth tissue · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…
1 finding from 1 review

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Restoration survival · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…
1 finding from 1 review

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Economic data: direct costs of materials and any reported associated indirect costs · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…

The review found no eligible studies for this question.

1 finding from 1 review

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Marginal integrity of restoration · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) showed no clear difference in marginal integrity of restorations compared with conventional mechanical caries removal (standard drill; handpiece…; GRADE not reported.

3 findings from 1 review

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Participant discomfort (vibration, smell, noise) · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)
1 finding from 1 review
  • Lasers for caries removal in deciduous and permanent teeth 2016 · Cochrane All outcomes
    during treatment
    Five studies reported participant discomfort (Belcheva 2014; Evans 2000; Hadley 2000; Keller 1998; Liu 2006). Keller 1998 (90 adults): discomfort significantly lower with laser (Analysis 1.6). Hadley 2000 (66 adults):…
    5 studies
    GRADE not reported

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Pulpal inflammation or necrosis · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)

It is very uncertain whether laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) changes pulpal inflammation or necrosis compared with conventional mechanical caries removal (standard drill; handpiece… (very low certainty).

3 findings from 1 review

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Restoration survival · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)

It is very uncertain whether laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) changes durability of restoration compared with conventional mechanical caries removal (standard drill; handpiece… (very low certainty).

3 findings from 1 review

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Operator preference/fatigue in operator · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)
1 finding from 1 review
  • One study (Evans 2000): 11 dental practitioners expressed a preference in 73 of 77 'dentist/patient encounters', significantly in favour of conventional drill rather than laser (P < 0.001); main difficulty with laser…
    1 study
    GRADE not reported

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Caries removal (clinical) · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) showed no clear difference in caries removal (clinical) compared with conventional mechanical caries removal (standard drill; handpiece… (low certainty).

1 finding from 1 review

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Duration of treatment · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) led to higher duration of treatment compared with conventional mechanical caries removal (standard drill; handpiece…; GRADE not reported.

1 finding from 1 review

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Other caries removal systems (chemo-mechanical, sono-abrasion, or air-abrasion)

Outcome not reported · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)

The review found no eligible studies for this question.

1 finding from 1 review
  • 'Types of interventions' allowed comparison of laser with other caries-removal systems (chemo-mechanical, sono-abrasion, air-abrasion); no included study used such a comparator (all nine included trials compared laser…
    Studies not reported
    No studies found

Fluoride mouthrinse (any fluoride agent, concentration, volume, frequency or technique; swished and expectorated, not swallowed) vs placebo or no treatment

Dental caries: dmfs increment (primary teeth) · Children and adolescents aged 16 years or less

The review found no eligible studies for this question.

1 finding from 1 review

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Secondary caries · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)
1 finding from 1 review
  • Lasers for caries removal in deciduous and permanent teeth 2016 · Cochrane All outcomes
    6 months to 2 years follow-up
    Two trials reported data on prevalence of secondary caries (Hadley 2000 at 6 months; Yazici 2010 at 2 years). No occurrence of caries was reported in either study (no events; no estimable effect).
    2 studies
    GRADE not reported

Fluoride mouthrinse (any fluoride agent, concentration, volume, frequency or technique; swished and expectorated, not swallowed) vs placebo or no treatment

Proportion developing new caries · Children and adolescents aged 16 years or less

Fluoride mouthrinse (any fluoride agent, concentration, volume,… showed no clear difference in proportion of children developing one or more new caries compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Fluoride mouthrinse (any fluoride agent, concentration, volume, frequency or technique; swished and expectorated, not swallowed) vs placebo or no treatment

Mucosal irritation / oral soft tissue allergic reaction (signs of sensitivity) · Children and adolescents aged 16 years or less
1 finding from 1 review

Fluoride mouthrinse (any fluoride agent, concentration, volume, frequency or technique; swished and expectorated, not swallowed) vs placebo or no treatment

Signs of acute toxicity during gel application (nausea, gagging, vomiting) · Children and adolescents aged 16 years or less

The review found no eligible studies for this question.

1 finding from 1 review