Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,138 questions · 1,154 findings · 139 reviews · Headline outcomes only

No studies found 184 · 15.9%GRADE not reported 183 · 15.9%Very low 273 · 23.7%Low 296 · 25.6%Moderate 171 · 14.8%High 47 · 4.1%

Intervention not reported

Adverse events · acute treatment of migraine in adolescents

The intervention probably leads to higher adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Pain freedom at 2 h · acute treatment of migraine in adolescents

The intervention probably leads to higher pain freedom at 2 h (moderate certainty).

1 finding from 1 review

Balneotherapy vs drug treatment

Improvement Global improvement on 5‐point scale (very good/good/fair/poor/very poor) · patients with rheumatoid arthritis

It is very uncertain whether balneotherapy changes improvement Global improvement on 5‐point scale (very… compared with drug treatment (very low certainty).

1 finding from 1 review